Breast cancer: Biology, biomarkers, and treatments
During the past recent years, various therapies emerged in the era of breast cancer. Breast
cancer is a heterogeneous disease in which genetic and environmental factors are involved …
cancer is a heterogeneous disease in which genetic and environmental factors are involved …
Cancer overdiagnosis: a biological challenge and clinical dilemma
For cancer screening to be successful, it should primarily detect cancers with lethal potential
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …
Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome
M Tkach, J Thalmensi, E Timperi… - Proceedings of the …, 2022 - National Acad Sciences
Tumor associated macrophages (TAMs), which differentiate from circulating monocytes, are
pervasive across human cancers and comprise heterogeneous populations. The …
pervasive across human cancers and comprise heterogeneous populations. The …
Breast cancer chemo-immunotherapy through liposomal delivery of an immunogenic cell death stimulus plus interference in the IDO-1 pathway
Immunotherapy provides the best approach to reduce the high mortality of metastatic breast
cancer (BC). We demonstrate a chemo-immunotherapy approach, which utilizes a liposomal …
cancer (BC). We demonstrate a chemo-immunotherapy approach, which utilizes a liposomal …
[HTML][HTML] Metabolic crosstalk in the breast cancer microenvironment
During tumorigenesis, breast tumour cells undergo metabolic reprogramming, which
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
[HTML][HTML] Overview of recent advances in metastatic triple negative breast cancer
D O'Reilly, M Al Sendi, CM Kelly - World journal of clinical oncology, 2021 - ncbi.nlm.nih.gov
Metastatic triple negative breast cancer (TNBC) has an aggressive phenotype with a
predilection for visceral organs and brain. Best responses to chemotherapy are …
predilection for visceral organs and brain. Best responses to chemotherapy are …
Molecular intrinsic versus clinical subtyping in breast cancer: A comprehensive review
A Szymiczek, A Lone, MR Akbari - Clinical genetics, 2021 - Wiley Online Library
Breast cancer is a heterogeneous disease manifesting diversity at the molecular,
histological and clinical level. The development of breast cancer classification was centered …
histological and clinical level. The development of breast cancer classification was centered …
Breast cancer immunotherapy: Current and novel approaches
K Barzaman, S Moradi-Kalbolandi… - International …, 2021 - Elsevier
The crucial role of the immune system in the progression/regression of breast cancer (BC)
should always be taken into account. Various immunotherapy approaches have been …
should always be taken into account. Various immunotherapy approaches have been …
High expression of cuproptosis-related SLC31A1 gene in relation to unfavorable outcome and deregulated immune cell infiltration in breast cancer: an analysis based …
Cuproptosis induction represents a promising alternative for immunotherapies and targeted
therapies in breast cancer. This study aimed to investigate the prognostic and biological …
therapies in breast cancer. This study aimed to investigate the prognostic and biological …
Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics
Y Cen, L Chen, Z Liu, Q Lin, X Fang, H Yao… - Cell death …, 2023 - nature.com
Therapy resistance remains a huge challenge for current breast cancer treatments.
Exploring molecular mechanisms of therapy resistance might provide therapeutic targets for …
Exploring molecular mechanisms of therapy resistance might provide therapeutic targets for …