[PDF][PDF] Benchmarking metagenomics tools for taxonomic classification

HY Simon, KJ Siddle, DJ Park, PC Sabeti - Cell, 2019 - cell.com
Metagenomic sequencing is revolutionizing the detection and characterization of microbial
species, and a wide variety of software tools are available to perform taxonomic …

[PDF][PDF] Childhood diarrhoeal diseases in developing countries

HU Ugboko, OC Nwinyi, SU Oranusi, JO Oyewale - Heliyon, 2020 - cell.com
Diarrhoeal diseases collectively constitute a serious public health challenge globally,
especially as the leading cause of death in children (after respiratory diseases). Childhood …

[HTML][HTML] The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

M Jain, HE Olsen, B Paten, M Akeson - Genome biology, 2016 - Springer
Nanopore DNA strand sequencing has emerged as a competitive, portable technology.
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …

[HTML][HTML] Critical assessment of metagenome interpretation—a benchmark of metagenomics software

A Sczyrba, P Hofmann, P Belmann, D Koslicki… - Nature …, 2017 - nature.com
Methods for assembly, taxonomic profiling and binning are key to interpreting metagenome
data, but a lack of consensus about benchmarking complicates performance assessment …

[HTML][HTML] Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

AL Greninger, SN Naccache, S Federman, G Yu… - Genome medicine, 2015 - Springer
We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus
(EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore …

MEGARes: an antimicrobial resistance database for high throughput sequencing

SM Lakin, C Dean, NR Noyes… - Nucleic acids …, 2017 - academic.oup.com
Antimicrobial resistance has become an imminent concern for public health. As methods for
detection and characterization of antimicrobial resistance move from targeted culture and …

Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery

S Bertrand, N Bohni, S Schnee, O Schumpp… - Biotechnology …, 2014 - Elsevier
Microorganisms have a long track record as important sources of novel bioactive natural
products, particularly in the field of drug discovery. While microbes have been shown to …

Burkholderia cepacia Complex Bacteria: a Feared Contamination Risk in Water-Based Pharmaceutical Products

M Tavares, M Kozak, A Balola… - Clinical microbiology …, 2020 - Am Soc Microbiol
Burkholderia cepacia (formerly Pseudomonas cepacia) was once thought to be a single
bacterial species but has expanded to the Burkholderia cepacia complex (Bcc), comprising …

[HTML][HTML] Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment

KR Chng, C Li, D Bertrand, AHQ Ng, JS Kwah… - Nature medicine, 2020 - nature.com
Although disinfection is key to infection control, the colonization patterns and resistomes of
hospital-environment microbes remain underexplored. We report the first extensive genomic …

Integration of distributed data processing platform with one or more distinct supporting platforms

H Timmerman, PGS Florissi - US Patent 10,541,938, 2020 - Google Patents
An apparatus in one embodiment comprises at least one processing device having a
processor coupled to a memory. The one or more processing devices are operative to …