Due to the fact that mRNA technology allows the production of diverse vaccines and
treatments in a shorter time frame and with reduced expense compared to conventional …

Messenger RNA (mRNA) has received great attention in the prevention and treatment of
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …

Although chimeric antigen receptor (CAR) T cells have altered the treatment landscape for B
cell malignancies, the risk of on-target, off-tumour toxicity has hampered their development …

Recently, chimeric antigen receptor (CAR)-T cell therapy has shown great promise in
treating haematological malignancies,,,,,–. However, CAR-T cell therapy currently has …

The steadfast advance of the synthetic biology field has enabled scientists to use genetically
engineered cells, instead of small molecules or biologics, as the basis for the development …

The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Chimeric antigen receptor T (CAR T) cell immunotherapy is successful at treating many
cancers. However, it often induces life-threatening cytokine release syndrome (CRS) and …

Due to their efficient recognition and lysis of malignant cells, natural killer (NK) cells are
considered as specialized immune cells that can be genetically modified to obtain capable …

Chimeric antigen receptor (CAR)-T cell therapy against T cell malignancies faces major
challenges including fratricide between CAR-T cells and product contamination from the …

Chimeric antigen receptors (CARs) are receptors for antigen that direct potent immune
responses. Tumor escape associated with low target antigen expression is emerging as one …