BRCA mutations in ovarian and prostate cancer: bench to bedside
Simple Summary DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …
Medical and surgical care of patients with mesothelioma and their relatives carrying germline BAP1 mutations
The most common malignancies that develop in carriers of BAP1 germline mutations include
diffuse malignant mesothelioma, uveal and cutaneous melanoma, renal cell carcinoma, and …
diffuse malignant mesothelioma, uveal and cutaneous melanoma, renal cell carcinoma, and …
The multicenter cancer of pancreas screening study: impact on stage and survival
PURPOSE To report pancreas surveillance outcomes of high-risk individuals within the
multicenter Cancer of Pancreas Screening-5 (CAPS5) study and to update outcomes of …
multicenter Cancer of Pancreas Screening-5 (CAPS5) study and to update outcomes of …
Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants
PURPOSE To provide precise age-specific risk estimates of cancers other than female
breast and ovarian cancers associated with pathogenic variants (PVs) in BRCA1 and …
breast and ovarian cancers associated with pathogenic variants (PVs) in BRCA1 and …
Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline☆
C Sessa, J Balmaña, SL Bober… - Annals of …, 2023 - annalsofoncology.org
Hereditary breast and ovarian cancer syndrome (HBOC) is clinically defined by family
history criteria, and molecularly defined by identification of germline pathogenic variants …
history criteria, and molecularly defined by identification of germline pathogenic variants …
Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2
PURPOSE To estimate the risk of contralateral breast cancer (CBC) among women with
germline pathogenic variants (PVs) in ATM, BRCA1, BRCA2, CHEK2, and PALB2 …
germline pathogenic variants (PVs) in ATM, BRCA1, BRCA2, CHEK2, and PALB2 …
Pancreatic cancer: changing epidemiology and new approaches to risk assessment, early detection, and prevention
EM Stoffel, RE Brand, M Goggins - Gastroenterology, 2023 - Elsevier
Pancreatic cancer usually results in poor survival with limited options for treatment, as most
affected individuals present with advanced disease. Early detection of preinvasive …
affected individuals present with advanced disease. Early detection of preinvasive …
Pancreatic Cancer Surveillance in Carriers of a Germline CDKN2A Pathogenic Variant: Yield and Outcomes of a 20-Year Prospective Follow-Up
DCF Klatte, B Boekestijn, MNJM Wasser… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Pancreatic cancer surveillance in high-risk individuals may lead to detection of
pancreatic ductal adenocarcinoma (PDAC) at an earlier stage and with improved survival …
pancreatic ductal adenocarcinoma (PDAC) at an earlier stage and with improved survival …
Comparison of mammography AI algorithms with a clinical risk model for 5-year breast cancer risk prediction: an observational study
VA Arasu, LA Habel, NS Achacoso, DSM Buist… - Radiology, 2023 - pubs.rsna.org
Background Although several clinical breast cancer risk models are used to guide screening
and prevention, they have only moderate discrimination. Purpose To compare selected …
and prevention, they have only moderate discrimination. Purpose To compare selected …
[HTML][HTML] Epithelial ovarian cancer
S Sambasivan - Cancer Treatment and Research Communications, 2022 - Elsevier
Epithelial ovarian cancer is the second commonest cause of death amongst all
gynaecological cancers. Treatment is challenging because almost 75% of cases are …
gynaecological cancers. Treatment is challenging because almost 75% of cases are …