Many phytochemicals with beneficial physiological activities have limited bioavailability due
to their poor solubility and stability characteristics. The bioactivities of phytochemicals could …

The roots, leaves, and seeds of Lepidium sativum L., popularly known as Garden cress in
different regions, have high economic importance; although, the crop is particularly …

Genistein, a polyphenolic isoflavone compound found abundantly in soy or soy‐based
products, is widely consumed in the Asian population. Genistein has poor bioavailability, to …

The rise of cancer immunotherapy, particularly the use of immune checkpoint inhibitors
(ICIs), has significantly changed the clinical treatment paradigm for patients with cancer. The …

The intake of hesperidin-rich sources, mostly found in orange juice, can decrease
cardiometabolic risk, potentially linked to the gut microbial phase-II hesperetin derivatives …

Neuroinflammation is a critical feature in the pathogenesis of neurodegenerative disorders
such as Alzheimer's disease (AD). Hesperetin can exert anti-inflammatory, antioxidant and …

The objective of this study was to investigate the effects of halophilic bacteria, including
Virgibacillus sp. ZV10-1, Virgibacillus sp. SK37, and Staphylococcus nepalensis JS11 as …

The low bioaccessibility of hesperetin and piperine hampers their application as therapeutic
agents. Piperine has the ability to improve the bioavailability of many compounds when co …

Flavonoids, a group of natural compounds with phenolic structure, are becoming popular as
alternative medicines obtained from plants. These compounds are reported to have various …

Ponciri Fructus is a crude drug obtained from the dried immature fruits of Poncirus trifoliata
(L). Raf.(Syn. Citrus trifoliata L.). This study aims to compile and analyze the ethnomedicinal …