Abstract p38 mitogen-activated protein kinases (P38α and β) and c-Jun N-terminal kinases
(JNK1, 2, and 3) are key mediators of the cellular stress response. However, prolonged P38 …

Acute respiratory distress syndrome (ARDS) is a common condition associated with critically
ill patients, characterized by bilateral chest radiographical opacities with refractory …

Acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI) are
heterogeneous conditions. The spatiotemporal evolution of these heterogeneities is …

Abstract Ginsenoside F 2 (F 2) is a potential bioactive metabolite of major ginsenosides. The
potential anti-cancer effect of F 2 in gastric cancer cells has not been appraised. This study …

Recent clinical research has revealed that mechanical ventilation (MV) can initiate
pulmonary fibrosis and induce mechanical ventilation-induced pulmonary fibrosis (MVPF) …

Mechanical ventilation (MV) performed in respiratory failure patients to maintain lung
function leads to ventilator-induced lung injury (VILI). This study investigates the role of …

Mechanical ventilation (MV) and oxygen therapy (hyperoxia; HO) comprise the cornerstones
of life-saving interventions for patients with acute respiratory distress syndrome (ARDS) …

Supportive mechanical ventilation is a necessary lifesaving treatment for acute respiratory
distress syndrome (ARDS). This intervention often leads to injury exacerbation by ventilator …

Apoptosis signal-regulating kinase 1 (ASK1), a member of the MAPK kinase kinase kinase
(MAP3K) family, is activated by various stimuli, which include oxidative stress, endoplasmic …

Ventilator-induced lung injury (VILI) is a serious acute injury to the lung tissue that can
develop during mechanical ventilation of patients. Due to the mechanical strain of …