The emerging potential of cold atmospheric plasma in skin biology

G Busco, E Robert, N Chettouh-Hammas… - Free Radical Biology …, 2020 - Elsevier
The maintenance of skin integrity is crucial to ensure the physiological barrier against
exogenous compounds, microorganisms and dehydration but also to fulfill social and …

PI3K/AKT/mTOR pathway in angiogenesis

J Karar, A Maity - Frontiers in molecular neuroscience, 2011 - frontiersin.org
The phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
pathway is activated in the majority of human cancers. This pathway is known to play a key …

[HTML][HTML] Exosomal lncRNA-H19 promotes osteogenesis and angiogenesis through mediating Angpt1/Tie2-NO signaling in CBS-heterozygous mice

J Behera, A Kumar, MJ Voor, N Tyagi - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Emerging evidence indicates that the growth of blood vessels and osteogenesis
is tightly coordinated during bone development. However, the molecular regulators of …

The role of astrocytes in neuroprotection after brain stroke: potential in cell therapy

A Becerra-Calixto, GP Cardona-Gómez - Frontiers in molecular …, 2017 - frontiersin.org
Astrocytes are commonly involved in negative responses through their hyperreactivity and
glial scar formation in excitotoxic and/or mechanical injuries. But, astrocytes are also …

[PDF][PDF] Physiological role of reactive oxygen species as promoters of natural defenses

J Roy, JM Galano, T Durand, JY Le Guennec… - FASEB …, 2017 - hal.umontpellier.fr
It has been 60 yr since the discovery of reactive oxygen species (ROS) in biology and the
beginning of the scientific community's attempt to understand the impact of the unpaired …

The role of nitric oxide in tumour progression

D Fukumura, S Kashiwagi, RK Jain - Nature Reviews Cancer, 2006 - nature.com
Nitric oxide (NO) and nitric oxide synthases are ubiquitous in malignant tumours and are
known to exert both pro-and anti-tumour effects. We summarize our current understanding of …

PI3K/PTEN signaling in angiogenesis and tumorigenesis

BH Jiang, LZ Liu - Advances in cancer research, 2009 - Elsevier
Phosphatidylinositol 3‐kinase (PI3K) and phosphatase and tensin homolog deleted on
chromosome 10 (PTEN) signaling pathway play an important role in multiple cellular …

Signaling and functions of angiopoietin-1 in vascular protection

NPJ Brindle, P Saharinen, K Alitalo - Circulation research, 2006 - Am Heart Assoc
Angiopoietin-1 (Ang1) has powerful vascular protective effects: suppressing plasma
leakage, inhibiting vascular inflammation, and preventing endothelial death. Preclinical …

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

SM Parikh, T Mammoto, A Schultz, HT Yuan… - PLoS …, 2006 - journals.plos.org
Background Acute respiratory distress syndrome (ARDS) is a devastating complication of
numerous underlying conditions, most notably sepsis. Although pathologic vascular leak …

Endothelial activation: the Ang/Tie axis in sepsis

A Leligdowicz, M Richard-Greenblatt, J Wright… - Frontiers in …, 2018 - frontiersin.org
Sepsis, a dysregulated host response to infection that causes life-threatening organ
dysfunction, is a highly heterogeneous syndrome with no specific treatment. Although sepsis …