Integrating plant molecular farming and materials research for next-generation vaccines

YH Chung, D Church, EC Koellhoffer, E Osota… - Nature Reviews …, 2022 - nature.com
Biologics—medications derived from a biological source—are increasingly used as
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …

Comparison of yeasts as hosts for recombinant protein production

AM Vieira Gomes, T Souza Carmo, L Silva Carvalho… - Microorganisms, 2018 - mdpi.com
Recombinant protein production emerged in the early 1980s with the development of
genetic engineering tools, which represented a compelling alternative to protein extraction …

Genetics on the Fly: A Primer on the Drosophila Model System

KG Hales, CA Korey, AM Larracuente, DM Roberts - Genetics, 2015 - academic.oup.com
Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …

Nutritional, functional and biological properties of insect proteins: Processes for obtaining, consumption and future challenges

RJS de Castro, A Ohara, JG dos Santos Aguilar… - Trends in food science & …, 2018 - Elsevier
Background Consuming insects as an alternative protein source is considered a future trend
and a viable strategy that could potentially contribute to global food security. Insects are a …

Baculovirus as versatile vectors for protein expression in insect and mammalian cells

TA Kost, JP Condreay, DL Jarvis - Nature biotechnology, 2005 - nature.com
Today, many thousands of recombinant proteins, ranging from cytosolic enzymes to
membrane-bound proteins, have been successfully produced in baculovirus-infected insect …

Bee viruses: Routes of infection in Hymenoptera

O Yañez, N Piot, A Dalmon, JR De Miranda… - Frontiers in …, 2020 - frontiersin.org
Numerous studies have recently reported on the discovery of bee viruses in different
arthropod species and their possible transmission routes, vastly increasing our …

Recombinant expression systems in the pharmaceutical industry

FR Schmidt - Applied microbiology and biotechnology, 2004 - Springer
In terms of downstream processing efficiency, secretory expression systems offer potential
advantages for the production of recombinant proteins, compared with inclusion body …

Factors involved in heterologous expression of proteins in E. coli host

M Pouresmaeil, S Azizi-Dargahlou - Archives of Microbiology, 2023 - Springer
The production of recombinant proteins is one of the most significant achievements of
biotechnology in the last century. These proteins are produced in the eukaryotic or …

Microalgae and cyanobacteria as enzyme biofactories

BSAF Brasil, FG de Siqueira, TFC Salum, CM Zanette… - Algal research, 2017 - Elsevier
Microalgae consist of a diverse group that includes prokaryotic cyanobacteria and
eukaryotic photosynthetic microorganisms that inhabit freshwater and marine habitats …

Recombinant protein vaccines produced in insect cells

MMJ Cox - Vaccine, 2012 - Elsevier
The baculovirus-insect cell expression system is a well known tool for the production of
complex proteins. The technology is also used for commercial manufacture of various …