BK polyomavirus: clinical aspects, immune regulation, and emerging therapies

GR Ambalathingal, RS Francis, MJ Smyth… - Clinical microbiology …, 2017 - Am Soc Microbiol
SUMMARY BK polyomavirus (BKV) causes frequent infections during childhood and
establishes persistent infections within renal tubular cells and the uroepithelium, with …

BK virus nephropathy in kidney transplantation: a state-of-the-art review

S Kant, A Dasgupta, S Bagnasco, DC Brennan - Viruses, 2022 - mdpi.com
BK virus maintains a latent infection that is ubiquitous in humans. It has a propensity for
reactivation in the setting of a dysfunctional cellular immune response and is frequently …

[HTML][HTML] The role of polyomaviruses in human disease

M Jiang, JR Abend, SF Johnson, MJ Imperiale - Virology, 2009 - Elsevier
The human polyomaviruses, BK virus and JC virus, have long been associated with serious
diseases including polyomavirus nephropathy and progressive multifocal …

Detection and monitoring of virus infections by real-time PCR

F Watzinger, K Ebner, T Lion - Molecular aspects of medicine, 2006 - Elsevier
The employment of polymerase chain reaction (PCR) techniques for virus detection and
quantification offers the advantages of high sensitivity and reproducibility, combined with an …

Treatment of polyomavirus infection in kidney transplant recipients: a systematic review

O Johnston, D Jaswal, JS Gill, S Doucette… - …, 2010 - journals.lww.com
Background. Polyomavirus-associated nephropathy (PVAN) is an important cause of kidney
graft loss but there is no consensus on its management. This study aimed to systematically …

BK virus nephropathy and kidney transplantation

DL Bohl, DC Brennan - Clinical Journal of the American Society of …, 2007 - journals.lww.com
Nephropathy from BK virus (BKV) infection is an evolving challenge in kidney transplant
recipients. It is the consequence of modern potent immunosuppression aimed at reducing …

BK and JC virus: a review

M Pinto, S Dobson - Journal of Infection, 2014 - Elsevier
Polyomaviruses are ubiquitous, species-specific viruses belonging to the family
Papovaviridae. The two most commonly known human polyomaviruses, BK virus and JC …

[HTML][HTML] BK virus in solid organ transplant recipients

HH Hirsch, P Randhawa… - American Journal of …, 2009 - Elsevier
The human polyomavirus BK (BKV) is linked to two major complications in transplant
recipients, polyomavirus-associated nephropathy (PyVAN)(1, 2, 3, 4) and polyomavirus …

The need for minimization strategies: current problems of immunosuppression

J Bamoulid, O Staeck, F Halleck… - Transplant …, 2015 - Wiley Online Library
New immunosuppressants and the better use of immunosuppressant combination therapy
have led to significant improvements in renal allograft outcomes over the last decades. Yet …

[HTML][HTML] BK virus infection in transplant recipients: an overview and update

P Randhawa, DC Brennan - American Journal of Transplantation, 2006 - Elsevier
BK virus infection after kidney transplantation has been a subject of great interest in the past
decade. This article traces the discovery of BK virus and the subsequent development of our …