Global consequences of liver ischemia/reperfusion injury
C Nastos, K Kalimeris, N Papoutsidakis… - Oxidative medicine …, 2014 - Wiley Online Library
Liver ischemia/reperfusion injury has been extensively studied during the last decades and
has been implicated in the pathophysiology of many clinical entities following hepatic …
has been implicated in the pathophysiology of many clinical entities following hepatic …
[HTML][HTML] Experimental and clinical evidence for modification of hepatic ischaemia–reperfusion injury by N-acetylcysteine during major liver surgery
S Jegatheeswaran, AK Siriwardena - HPB, 2011 - Elsevier
Background Hepatic ischaemia–reperfusion (I/R) injury occurs in both liver resectional
surgery and in transplantation. The biochemistry of I/R injury involves short-lived oxygen free …
surgery and in transplantation. The biochemistry of I/R injury involves short-lived oxygen free …
Modelling winter organic aerosol at the European scale with CAMx: evaluation and source apportionment with a VBS parameterization based on novel wood burning …
G Ciarelli, S Aksoyoglu, I El Haddad… - Atmospheric …, 2017 - acp.copernicus.org
We evaluated a modified VBS (volatility basis set) scheme to treat biomass-burning-like
organic aerosol (BBOA) implemented in CAMx (Comprehensive Air Quality Model with …
organic aerosol (BBOA) implemented in CAMx (Comprehensive Air Quality Model with …
N‐acetylcysteine effects on genotoxic and oxidative stress parameters in cirrhotic rats with hepatopulmonary syndrome
R Vercelino, J Tieppo, AS Dias… - Basic & clinical …, 2008 - Wiley Online Library
The aim of this study was to evaluate the potential antioxidant effects of N‐acetylcysteine in
hepatopulmonary syndrome, a complication of cirrhosis, using an experimental model of …
hepatopulmonary syndrome, a complication of cirrhosis, using an experimental model of …
Antioxidant treatment attenuates intestinal mucosal damage and gut barrier dysfunction after major hepatectomy. Study in a porcine model
C Nastos, K Kalimeris, N Papoutsidakis… - Journal of …, 2011 - Elsevier
Background This study aims to evaluate whether injury of gut mucosa in a porcine model of
post-hepatectomy liver dysfunction can be prevented using antioxidant treatment with …
post-hepatectomy liver dysfunction can be prevented using antioxidant treatment with …
[HTML][HTML] Dynamic changes and mechanism of intestinal endotoxemia in partially hepatectomized rats
CP Xu, J Liu, JC Liu, DW Han, Y Zhang… - World Journal of …, 2007 - ncbi.nlm.nih.gov
AIM: To explore the mechanism of intestinal endo-toxemia (IETM) formation and its changes
in partially hepatectomized (PH) rats. METHODS: One-hundred and two adult male Wistar …
in partially hepatectomized (PH) rats. METHODS: One-hundred and two adult male Wistar …
N-acetylcysteine may prevent severe intestinal damage in necrotizing enterocolitis
C Tayman, A Tonbul, A Kosus, IM Hirfanoglu… - Journal of Pediatric …, 2012 - Elsevier
OBJECTIVE: The aim of this study was to evaluate the preventive effect of N-acetylcysteine
(NAC) on the development of necrotizing enterocolitis (NEC) in an experimental rat model …
(NAC) on the development of necrotizing enterocolitis (NEC) in an experimental rat model …
Intestinal barrier function in response to abundant or depleted mucosal glutathione in Salmonella-infected rats
MTJ Van Ampting, AJ Schonewille, C Vink… - BMC physiology, 2009 - Springer
Background Glutathione, the main antioxidant of intestinal epithelial cells, is suggested to
play an important role in gut barrier function and prevention of inflammation-related …
play an important role in gut barrier function and prevention of inflammation-related …
Clinical results of N-acetylcysteine after major hepatic surgery: a review
A McKay, D Cassidy, F Sutherland, E Dixon - Journal of hepato-biliary …, 2008 - Springer
Abstract Background/Purpose Ischemia/reperfusion injury is thought to play an important
role in postoperative liver dysfunction and morbidity following major liver surgery. N …
role in postoperative liver dysfunction and morbidity following major liver surgery. N …
The potential role of efficacy and safety evaluation of N-acetylcysteine administration during liver procurement. The NAC-400 single center randomized controlled trial
C Gómez-Gavara, Á Moya-Herraiz, D Hervás… - …, 2021 - journals.lww.com
Background. N-acetylcysteine infusions have been widely used to reduce
ischemia/reperfusion damage to the liver; however, convincing evidence of their benefits is …
ischemia/reperfusion damage to the liver; however, convincing evidence of their benefits is …