Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans

S Ramakrishnan, M Serricchio, B Striepen… - Progress in Lipid …, 2013 - Elsevier
Lipid metabolism is of crucial importance for pathogens. Lipids serve as cellular building
blocks, signalling molecules, energy stores, posttranslational modifiers, and pathogenesis …

Yeast as a potential vehicle for neglected tropical disease drug discovery

PW Denny, PG Steel - Journal of Biomolecular Screening, 2015 - journals.sagepub.com
High-throughput screening (HTS) efforts for neglected tropical disease (NTD) drug discovery
have recently received increased attention because several initiatives have begun to …

Characterising kinetoplastid pantothenate kinase, a multifunctional enzyme of the CoA biosynthesis pathway

RB Roscoe - 2023 - researchonline.lshtm.ac.uk
Kinetoplastid parasites of the Trypanosoma and Leishmania genera cause fatal diseases of
the tropics, subtropics and Mediterranean basin, in the form of Human African …

Caracterização do metabolismo de ácidos graxos em Trypanosoma cruzi.

ROO Souza - 2019 - teses.usp.br
Está bem estabelecido que o metabolismo do T. cruzi, agente etiológico da doença de
Chagas, é baseado principalmente no consumo de glicose e/ou aminoácidos, dependendo …

Patent Highlights February–March 2017

HAM Mucke - Pharmaceutical Patent Analyst, 2017 - Taylor & Francis
VX), agricultural pesticides (paraoxon, parathion, tetraethyl pyrophosphate, and dozens of
others) claim a far larger human toll, especially when used by insufficiently trained and …