Vaccine process technology—A decade of progress

B Buckland, G Sanyal, T Ranheim… - Biotechnology and …, 2024 - Wiley Online Library
In the past decade, new approaches to the discovery and development of vaccines have
transformed the field. Advances during the COVID‐19 pandemic allowed the production of …

Cell-free systems for a multi-pronged approach to next-generation therapeutics and diagnostics

KJ Kim, SJ Lee, DM Kim - Biotechnology and Bioprocess Engineering, 2024 - Springer
Effective diagnostics and therapeutics are foundational to modern medical technology. As
the drug modality transitions from traditional small-molecule drugs to more intricate protein …

Synthesis of secretory leukocyte protease inhibitor using cell-free protein synthesis system

Y Hiroshima, R Kido, J Kido, M Bando, K Yoshida… - Odontology, 2024 - Springer
Secretory leukocyte protease inhibitor (SLPI) functions as a protease inhibitor that
modulates excessive proteolysis in the body, exhibits broad-spectrum antimicrobial activity …

Inexpensive and colorimetric RNA detection at ambient temperature with a cell-free protein synthesis platform

ÖD Toparlak, M Notarangelo, A Quattrone… - … for Sustainable Materials, 2024 - Springer
While many proposals of paper-based diagnostics utilize cell-free gene expression systems,
these assays oftentimes suffer from the need for temperature cycling and high operational …