[HTML][HTML] Alzheimer's disease as a viral disease: Revisiting the infectious hypothesis
Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …
Overwhelming evidence for a major role for herpes simplex virus type 1 (HSV1) in Alzheimer's disease (AD); underwhelming evidence against
RF Itzhaki - Vaccines, 2021 - mdpi.com
This review describes investigations of specific topics that lie within the general subject of
HSV1's role in AD/dementia, published in the last couple of years. They include studies on …
HSV1's role in AD/dementia, published in the last couple of years. They include studies on …
Human herpesviruses 6A and 6B in brain diseases: association versus causation
AL Komaroff, PE Pellett, S Jacobson - Clinical microbiology …, 2020 - Am Soc Microbiol
SUMMARY Human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B),
collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans …
collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans …
[HTML][HTML] Evidence supportive of a bacterial component in the etiology for Alzheimer's disease and for a temporal-spatial development of a pathogenic microbiome in …
Background Over the last few decades, a growing body of evidence suggests a role for
various infectious agents in Alzheimer's Disease (AD) pathogenesis. Despite diverse …
various infectious agents in Alzheimer's Disease (AD) pathogenesis. Despite diverse …
The viral hypothesis: how herpesviruses may contribute to Alzheimer's disease
The hypothesis that infectious agents, particularly herpesviruses, contribute to Alzheimer's
disease (AD) pathogenesis has been investigated for decades but has long engendered …
disease (AD) pathogenesis has been investigated for decades but has long engendered …
The Role of Human Herpesvirus 6 Infection in Alzheimer's Disease Pathogenicity—A Theoretical Mosaic
C Romanescu, TG Schreiner, I Mukovozov - Journal of Clinical Medicine, 2022 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative disorder generally affecting older adults, is
the most common form of dementia worldwide. The disease is marked by severe cognitive …
the most common form of dementia worldwide. The disease is marked by severe cognitive …
The electronic tree of life (eToL): a net of long probes to characterize the microbiome from RNA-seq data
X Hu, JG Haas, R Lathe - BMC microbiology, 2022 - Springer
Background Microbiome analysis generally requires PCR-based or metagenomic shotgun
sequencing, sophisticated programs, and large volumes of data. Alternative approaches …
sequencing, sophisticated programs, and large volumes of data. Alternative approaches …
Controversial role of herpesviruses in Alzheimer's disease
R Rizzo - PLoS pathogens, 2020 - journals.plos.org
The controversial hypothesis that microbes might trigger Alzheimer's disease (AD) has been
debated for decades. Around 30 years ago, researchers in the United Kingdom discovered …
debated for decades. Around 30 years ago, researchers in the United Kingdom discovered …
The remarkable complexity of the brain microbiome in health and disease
X Hu, CA Mckenzie, C Smith, JG Haas, R Lathe - biorxiv, 2023 - biorxiv.org
Microbes in human brain and their potential contribution to neurodegenerative conditions
such as Alzheimer's disease (AD) have long been debated. We recently developed a new …
such as Alzheimer's disease (AD) have long been debated. We recently developed a new …
Activation of endogenous retrovirus, brain infections and environmental insults in neurodegeneration and Alzheimer's disease
F Licastro, E Porcellini - International Journal of Molecular Sciences, 2021 - mdpi.com
Chronic neurodegenerative diseases are complex, and their pathogenesis is uncertain.
Alzheimer's disease (AD) is a neurodegenerative brain alteration that is responsible for most …
Alzheimer's disease (AD) is a neurodegenerative brain alteration that is responsible for most …