Quercetin derivatives: Drug design, development, and biological activities, a review
SR Alizadeh, MA Ebrahimzadeh - European journal of medicinal chemistry, 2022 - Elsevier
More studies are needed to develop new drugs for problems associated with drug
resistance and unfavorable side effects. The natural flavonoid of quercetin revealed a wide …
resistance and unfavorable side effects. The natural flavonoid of quercetin revealed a wide …
Drug design strategies that aim to improve the low solubility and poor bioavailability conundrum in quercetin derivatives
SR Alizadeh, N Savadkouhi… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Scientists are especially interested in polyphenols, particularly flavonoids.
Quercetin, a flavonoid, has demonstrated various therapeutic properties, such as …
Quercetin, a flavonoid, has demonstrated various therapeutic properties, such as …
Asymmetric counter-anion-directed aminomethylation: synthesis of chiral β-amino acids via trapping of an enol intermediate
A novel enantioselective aminomethylation reaction of diazo compound, alcohol and α-
aminomethyl ether enabled by asymmetric counteranion-directed catalysis is disclosed that …
aminomethyl ether enabled by asymmetric counteranion-directed catalysis is disclosed that …
[HTML][HTML] Synthesis and antibacterial and antiviral activities of myricetin derivatives containing a 1, 2, 4-triazole Schiff base
Y Chen, P Li, S Su, M Chen, J He, L Liu, M He… - RSC …, 2019 - pubs.rsc.org
A series of novel myricetin derivatives containing a 1, 2, 4-triazole Schiff base were
designed and synthesized. Their structures were systematically characterized using 1H …
designed and synthesized. Their structures were systematically characterized using 1H …
Anticancer activity of Mannich bases: a review of recent literature
G Roman - ChemMedChem, 2022 - Wiley Online Library
This report summarizes the latest published data on the antiproliferative action and cytotoxic
activity of Mannich bases, a structurally heterogeneous category of chemical entities that …
activity of Mannich bases, a structurally heterogeneous category of chemical entities that …
Sonchus oleraceus Linn protects against LPS-induced sepsis and inhibits inflammatory responses in RAW264. 7 cells
L Chen, X Lin, J Xiao, Y Tian, B Zheng… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Sonchus oleraceus Linn (SOL) belongs to family
of Asteraceae, is a traditional medicinal plant, which has been used to treat tumor …
of Asteraceae, is a traditional medicinal plant, which has been used to treat tumor …
A facile and efficient synthesis of benzimidazole as potential anticancer agents
TKC Huynh, THA Nguyen, NHS Tran… - Journal of Chemical …, 2020 - Springer
This study reports a simple process to synthesize and separate of 2-(substituted-phenyl)
benzimidazole derivatives with high yield and efficiency. Specifically, by reacting ortho …
benzimidazole derivatives with high yield and efficiency. Specifically, by reacting ortho …
[HTML][HTML] Design and simulation of a resonant nanoring-based two-dimensional photonic crystal biosensor for cancer cell detection
This article introduces a novel two-dimensional photonic crystal biosensor designed for the
detection of various cancer cell types and the verification of associated parameters. The …
detection of various cancer cell types and the verification of associated parameters. The …
[HTML][HTML] Quercetin hybrids—Synthesis, spectral characterization and radical scavenging potential
D Kirkova, Y Stremski, S Statkova-Abeghe, M Docheva - Molbank, 2022 - mdpi.com
New quercetin-based derivatives are synthesized in an easily accessible one-pot manner.
The method is based on the reaction of quercetin with in situ formed electrophilic N …
The method is based on the reaction of quercetin with in situ formed electrophilic N …
Copper-catalyzed borylative aminomethylation of C–C double and triple bonds with N, O-acetal
X Qiu, L Xu, S Wang, Y Dai, Y Feng, C Gong… - Chemical …, 2021 - pubs.rsc.org
A copper-catalyzed borylaminomethylation of multiple carbon–carbon bonds with N, O-
acetal and bis (pinacolato) diboron has been disclosed that offers efficient and expedient …
acetal and bis (pinacolato) diboron has been disclosed that offers efficient and expedient …