Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Ferroptosis, a type of regulated cell death driven by iron-dependent phospholipid
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …

Ferroptosis is a form of iron‐dependent regulated cell death characterized by the
accumulation of toxic lipid peroxides, particularly in the plasma membrane, leading to lytic …

Regulation of cell mortality for disease treatment has been the focus of research. Ferroptosis
is an iron-dependent regulated cell death whose mechanism has been extensively studied …

In the context of myocardial infarction, the burst of superoxide generated by reverse electron
transport (RET) at complex I in mitochondria is a crucial trigger for damage during …

Ferroptosis has attracted attention throughout the last decade because of its tremendous
clinical importance. Here, we review the rapidly growing body of literature on how inhibition …

Pressure overload–induced cardiac hypertrophy is a common cause of heart failure (HF),
and emerging evidence suggests that excessive oxidized lipids have a detrimental effect on …

Doxorubicin (DOX) is an effective anticancer agent, but its clinical utility is constrained by
dose‐dependent cardiotoxicity, partly due to cardiomyocyte ferroptosis. However, the …

Rationale Myocardial ischemia/reperfusion (I/R) injury is characterized by cell death via
various cellular mechanisms upon reperfusion. As a new type of cell death, ferroptosis …

Acute myocardial infarction, characterized by high morbidity and mortality, has now become
a serious health hazard for human beings. Conventional surgical interventions to restore …