Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …

The global prevalence of diabetes mellitus and Alzheimer's disease is increasing alarmingly
with the aging of the population. Numerous epidemiological data suggest that there is a …

Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

Early and progressive dysfunctions of the dopaminergic system from the Ventral Tegmental
Area (VTA) have been described in Alzheimer's Disease (AD). During the long pre …

Neurodegenerative diseases (NDs) affect millions of people worldwide, and to date,
Alzheimer's and Parkinson's diseases are the most common NDs. Of the many risk factors …

Alzheimer's Disease (AD) is a global chronic disease in adults with beta-amyloid (Aβ)
deposits and hyperphosphorylated tau protein as the pathologic characteristics. Although …

Alzheimer's disease (AD) is a complex and heterogeneous neurodegenerative disorder with
contributions from multiple pathophysiological pathways. One of the long-recognized and …

The disease-specific accumulation of pathological proteins has long been the major focus of
research in neurodegenerative diseases (ND), including Alzheimer's disease (AD) and …

The most prevalent type of dementia, Alzheimer's disease (AD), is a compelling illustration of
the link between cognitive deficits and neurophysiological anomalies. We investigated the …

Most mitochondrial proteins are targeted to the organelle by N-terminal mitochondrial
targeting sequences (MTSs, or “presequences”) that are recognized by the import machinery …