Glioma stem cells: novel data obtained by single-cell sequencing

A Gisina, I Kholodenko, Y Kim, M Abakumov… - International journal of …, 2022 - mdpi.com
Glioma is the most common type of primary CNS tumor, composed of cells that resemble
normal glial cells. Recent genetic studies have provided insight into the inter-tumoral …

Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Simplifying synthesis of the expanding glioblastoma literature: a topic modeling approach

M Karabacak, P Jagtiani, A Carrasquilla, A Jain… - Journal of Neuro …, 2024 - Springer
Purpose Our study aims to discover the leading topics within glioblastoma (GB) research,
and to examine if these topics have “hot” or “cold” trends. Additionally, we aim to showcase …

Unlocking glioblastoma secrets: natural killer cell therapy against cancer stem cells

Y Du, KE Pollok, J Shen - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma (GBM) is an aggressive brain tumor that is heterogenous at
the cellular and molecular levels. It deftly invades the brain parenchyma making it …

Regulation of cancer stem cells and immunotherapy of glioblastoma

А Kosianova, O Pak… - Biomedical …, 2023 - spandidos-publications.com
Glioblastoma (GB) is one of the most adverse diagnoses in oncology. Complex current
treatment results in a median survival of 15 months. Resistance to treatment is associated …

Multifocal and multicentric glioblastoma: Imaging signature, molecular characterization, patterns of spread, and treatment

M Farhat, GN Fuller, M Wintermark… - The Neuroradiology …, 2023 - journals.sagepub.com
Multifocal and multicentric glioblastoma (GBM) or collectively, m-GBM, is an imaging
diagnosis present in up to 34% of patients with GBM. Compared to unifocal disease, patients …

Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma

YL Cheng, MA Banu, W Zhao, SS Rosenfeld, P Canoll… - Cell reports, 2024 - cell.com
Glioblastoma (GBM) is a deadly brain tumor, and the kinesin motor KIF11 is an attractive
therapeutic target with roles in proliferation and invasion. Resistance to KIF11 inhibitors …

[HTML][HTML] Are we better together? Addressing a combined treatment of pitavastatin and temozolomide for brain cancer

J Basso, AM Matos, S Ghavami, A Fortuna… - European Journal of …, 2024 - Elsevier
Pitavastatin is commonly prescribed to treat hypercholesterolemia through the regulation of
cholesterol biosynthesis. Interestingly, it has also demonstrated a great potential for treating …

ImmunoPET imaging–based pharmacokinetic profiles of an antibody and its Fab targeting endothelin A receptors on glioblastoma stem cells in a preclinical orthotopic …

M Hautiere, D Vivier, D Pineau, C Denis… - European Journal of …, 2023 - Springer
Background The resistance of glioblastoma stem cells (GSCs) to treatment is one of the
causes of glioblastoma (GBM) recurrence. Endothelin A receptor (ETA) overexpression in …

Nanotechnology Meets Stem Cell Therapy for Treating Glioblastomas: A Review

AK Ghosh, A Ghosh, PK Das - ACS Applied Nano Materials, 2024 - ACS Publications
Malignant glioblastoma, also known as Glioblastoma multiforme (GBM), is one of the most
aggressive subtypes, characterized by wide vascularization and complex invasion. The …