A review of epigenetic contributions to post-traumatic stress disorder

H Howie, CM Rijal, KJ Ressler - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
Post-traumatic stress disorder (PTSD) is a syndrome which serves as a classic example of
psychiatric disorders that result from the intersection of nature and nurture, or gene and …

Sex differences in post-traumatic stress disorder risk: autonomic control and inflammation

IT Fonkoue, V Michopoulos, J Park - Clinical Autonomic Research, 2020 - Springer
Aim Over 7 million US adults and about 20% of the military population have post-traumatic
stress disorder (PTSD), a debilitating condition that is independently linked to a significantly …

Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and …

S Katrinli, AX Maihofer, AH Wani, JR Pfeiffer… - Molecular …, 2022 - nature.com
Epigenetic factors modify the effects of environmental factors on biological outcomes.
Identification of epigenetic changes that associate with PTSD is therefore a crucial step in …

[HTML][HTML] An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

MW Logue, MW Miller, EJ Wolf, BR Huber… - Clinical …, 2020 - Springer
Background Previous studies using candidate gene and genome-wide approaches have
identified epigenetic changes in DNA methylation (DNAm) associated with posttraumatic …

[HTML][HTML] Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in US military veterans

JL Montalvo-Ortiz, J Gelernter, Z Cheng… - Translational …, 2022 - nature.com
Posttraumatic stress disorder (PTSD) is a chronic and disabling psychiatric disorder
prevalent in military veterans. Epigenetic mechanisms have been implicated in the etiology …

[HTML][HTML] A narrative review of the epigenetics of post-traumatic stress disorder and post-traumatic stress disorder treatment

L Cao-Lei, D Saumier, J Fortin, A Brunet - Frontiers in psychiatry, 2022 - frontiersin.org
Epigenetic research in post-traumatic stress disorder (PTSD) is essential, given that
environmental stressors and fear play such a crucial role in its development. As such, it may …

Proton Magnetic Resonance Spectroscopy in Post-Traumatic Stress Disorder—Updated Systematic Review and Meta-Analysis

KM Swanberg, L Campos, CG Abdallah… - Chronic …, 2022 - journals.sagepub.com
A stressor-related disorder wherein traumatic experience precipitates protracted disruptions
to mood and cognition, post-traumatic stress disorder (PTSD) is associated with wide …

Integration of peripheral transcriptomics, genomics, and interactomics following trauma identifies causal genes for symptoms of post-traumatic stress and major …

S Wuchty, AJ Myers, M Ramirez-Restrepo… - Molecular …, 2021 - nature.com
Posttraumatic stress disorder (PTSD) is a debilitating syndrome with substantial morbidity
and mortality that occurs in the aftermath of trauma. Symptoms of major depressive disorder …

PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L

S Katrinli, Y Zheng, A Gautam, R Hammamieh… - Brain, behavior, and …, 2021 - Elsevier
Posttraumatic stress disorder (PTSD) is characterized by intrusive thoughts, avoidance,
negative alterations in cognitions and mood, and arousal symptoms that adversely affect …

[HTML][HTML] Genome-wide differentially methylated genes associated with posttraumatic stress disorder and longitudinal change in methylation in rape survivors

J Nöthling, N Abrahams, S Toikumo… - Translational …, 2021 - nature.com
Rape is associated with a high risk for posttraumatic stress disorder (PTSD). DNA
methylation changes may confer risk or protection for PTSD following rape by regulating the …