Abnormally phosphorylated tau, an indicator of Alzheimer's disease, accumulates in the first
decades of life in the locus coeruleus (LC), the brain's main noradrenaline supply. However …

Neuromelanin-sensitive MRI is a burgeoning non-invasive neuroimaging method with an
increasing number of applications in psychiatric research. This MRI modality is sensitive to …

Abstract Changes in dopaminergic neuromodulation play a key role in adult memory
decline. Recent research has also implicated noradrenaline in shaping late-life memory …

Emotional arousal is known to enhance episodic memory in young adults. However,
compared to valence, little is known about how healthy aging impacts arousal-enhanced …

The locus coeruleus (LC), our main source of norepinephrine (NE) in the brain, declines with
age and is a potential epicentre of protein pathologies in neurodegenerative diseases (ND) …

Following the development of magnetic resonance imaging (MRI) methods to assay the
integrity of catecholamine nuclei, including the locus coeruleus (LC), there has been an …

The locus coeruleus is critical for selective information processing by modulating the brain's
connectivity configuration. Increasingly, studies have suggested that LC controls sensory …

Study objective Finding typical patterns-phenotypes-of sleep behaviors characterizing
parasomnias in different age and sex groups. Methods We analyzed YouTube videos on …

Physiological arousal affects attention and memory, sometimes enhancing and other times
impairing what we attend to and remember. In the present study, we investigated how …

Age-related impairments in value representations and updating during decision-making and
reward-based learning are often related to age-related attenuation in the catecholamine …