[HTML][HTML] Recent advances on quinazoline derivatives: A potential bioactive scaffold in medicinal chemistry
This paper intended to explore and discover recent therapeutic agents in the area of
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
[HTML][HTML] Medicinal chemistry of quinazolines as analgesic and anti-inflammatory agents
MF Zayed - ChemEngineering, 2022 - mdpi.com
Quinazoline is an essential scaffold, known to be linked with various biological activities.
Some of the prominent biological activities of this system are analgesic, anti-inflammatory …
Some of the prominent biological activities of this system are analgesic, anti-inflammatory …
Current perspectives on quinazolines with potent biological activities: A review
Quinazoline is a heterocyclic compound having biological activities. It is aromatic in nature
having bicyclic structure containing benzene ring and pyrimidine ring. Quinazoline and its …
having bicyclic structure containing benzene ring and pyrimidine ring. Quinazoline and its …
Quinazoline: An update on current status against convulsions
RS Cheke, SD Shinde, JP Ambhore… - Journal of Molecular …, 2022 - Elsevier
Epilepsy is one of the most frequent chronic neurological disorder extremely threatening the
life and good health. More than 70 million individuals suffering from epilepsy worldwide and …
life and good health. More than 70 million individuals suffering from epilepsy worldwide and …
Synthesis of Quinazolines from N,N′-Disubstituted Amidines via I2/KI-Mediated Oxidative C–C Bond Formation
Z Lv, B Wang, Z Hu, Y Zhou, W Yu… - The Journal of Organic …, 2016 - ACS Publications
An I2/KI-promoted oxidative C–C bond formation reaction from C (sp 3)–H and C (sp 2)–H
bonds has been used to construct quinazoline skeletons from N, N′-disubstituted amidines …
bonds has been used to construct quinazoline skeletons from N, N′-disubstituted amidines …
Quinazoline compounds for antitumor treatment
GI Solyanik - Experimental oncology, 2019 - exp-oncology.com.ua
Quinazolines are among the most useful heterocyclic compounds due to their diverse
chemical reactivity and a wide range of biological activity. Despite a large number of …
chemical reactivity and a wide range of biological activity. Despite a large number of …
Synthesis of quinazolines via an iron-catalyzed oxidative amination of N–H ketimines
C Chen, F He, G Tang, H Yuan, N Li… - The Journal of …, 2018 - ACS Publications
An efficient synthesis of quinazolines based on an iron-catalyzed C (sp3)-H oxidation and
intramolecular C–N bond formation using tert-BuOOH as the terminal oxidant is described …
intramolecular C–N bond formation using tert-BuOOH as the terminal oxidant is described …
One-Pot Synthesis of Trifluoromethylated Quinazolin-4(3H)-ones with Trifluoroacetic Acid as CF3 Source
S Almeida, R Marti, E Vanoli, S Abele… - The Journal of organic …, 2018 - ACS Publications
A novel and convenient one-pot sequential cascade method for the preparation of 2-
trifluoromethylquinazolin-4 (3 H)-ones is described. Trifluoroacetic acid (TFA) was employed …
trifluoromethylquinazolin-4 (3 H)-ones is described. Trifluoroacetic acid (TFA) was employed …
[HTML][HTML] Quinazolino-thiadiazoles as antimicrobial agents
In the present research, we report the synthesis and in vitro antimicrobial activity of a new
series of novel quinazolino-thiadiazoles as fused pharmacophore (3–20). In general, the …
series of novel quinazolino-thiadiazoles as fused pharmacophore (3–20). In general, the …
[HTML][HTML] Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3 (4H)-yl) methyl) pyridin-1-ium derivatives (BOPs) as potential dual …
Abstract Alzheimer's disease (AD), is among the most growing neurodegenerative diseases,
which is mainly caused by the acetylcholine neurotransmitter loss in the hippocampus and …
which is mainly caused by the acetylcholine neurotransmitter loss in the hippocampus and …