Immune-related adverse events of checkpoint inhibitors

M Ramos-Casals, JR Brahmer, MK Callahan… - Nature reviews Disease …, 2020 - nature.com
Cancer immunotherapies have changed the landscape of cancer treatment during the past
few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and …

An update on the pathogenesis of Hashimoto's thyroiditis

AP Weetman - Journal of endocrinological investigation, 2021 - Springer
It is 70 years since Noel Rose embarked on his pioneering studies that lead to the discovery
of autoimmune thyroiditis and the elucidation of Hashimoto's thyroiditis. This short review to …

Thyroid immune-related adverse events following immune checkpoint inhibitor treatment

CA Muir, RJ Clifton-Bligh, GV Long… - The Journal of …, 2021 - academic.oup.com
Context Thyroid dysfunction occurs commonly following immune checkpoint inhibition. The
etiology of thyroid immune-related adverse events (irAEs) remains unclear and clinical …

Adrenal insufficiency

S Hahner, RJ Ross, W Arlt, I Bancos… - Nature Reviews …, 2021 - nature.com
Adrenal insufficiency (AI) is a condition characterized by an absolute or relative deficiency of
adrenal cortisol production. Primary AI (PAI) is rare and is caused by direct adrenal failure …

[PDF][PDF] Clinical characteristics and treatment of immune-related adverse events of immune checkpoint inhibitors

J Choi, SY Lee - Immune network, 2020 - synapse.koreamed.org
Immune checkpoint inhibitors (ICIs) have been changing the paradigm of cancer treatment.
However, immune-related adverse effects (irAEs) have also increased with the exponential …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) consensus definitions for immune checkpoint inhibitor-associated immune-related adverse events (irAEs) …

J Naidoo, C Murphy, MB Atkins… - … for immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Immune-related adverse events (irAEs) associated with immune checkpoint inhibitor (ICI)
therapy may vary substantially in their clinical presentation, including natural history …

A review of cancer immunotherapy toxicity: immune checkpoint inhibitors

N Chhabra, J Kennedy - Journal of Medical Toxicology, 2021 - Springer
Cancer immunotherapy, which leverages features of the immune system to target neoplastic
cells, has revolutionized the treatment of cancer. The use of these therapies has rapidly …

PD-L1 inhibitor-induced thyroiditis is associated with better overall survival in cancer patients

A Kotwal, L Kottschade, M Ryder - Thyroid, 2020 - liebertpub.com
Background: Thyroid immune-related adverse events (IRAEs) have been reported more
frequently with programmed cell death protein-1 (PD-1) inhibitors than cytotoxic T …

Hyperglycemic crises in adults with diabetes: a consensus report

GE Umpierrez, GM Davis, NA ElSayed… - Diabetes …, 2024 - diabetesjournals.org
The American Diabetes Association (ADA), European Association for the Study of Diabetes
(EASD), Joint British Diabetes Societies for Inpatient Care (JBDS), American Association of …

Holistic approach to immune checkpoint inhibitor-related adverse events

R Poto, T Troiani, G Criscuolo, G Marone… - Frontiers in …, 2022 - frontiersin.org
Immune checkpoint inhibitors (ICIs) block inhibitory molecules, such as cytotoxic T-
lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1), or its …