Cancer is the second highest cause of death worldwide. Several therapeutic approaches,
such as conventional chemotherapy, antibodies and small molecule inhibitors and …

Several researchers have reported the use of cholesterol-based carriers in drug delivery.
The presence of cholesterol in cell membranes and its wide distribution in the body has led …

Combination therapy involving chemotherapeutic drugs and genes is emerging as a
promising strategy to provide a synergistic therapeutic effect, to overcome drug resistance …

Topoisomerase I (Topo I) is a nuclear enzyme engaged in adjustment of DNA topological
structure during cell cycle by cleaving and reannealing one of the two strands of the DNA …

The use of 3D printing technology in the manufacturing of drug delivery systems has
expanded and benefit of a customized care. The ability to create tailor-made structures filled …

A novel amphiphilic pH-sensitive triblock polymer brush (poly (β-amino esters)-g-
cholesterol)-b-poly (ethylene glycol)-b-(poly (β-amino esters)-g-cholesterol)((PAE-g-Chol)-b …

Stimuli-responsive nanocarriers have attracted increased attention as materials that can
facilitate drug and gene delivery in cancer therapy. The present study reports the …

The cellular environment offers some unique features to carry out polymerizations under
controlled conditions. Polymerization of monomers in cellular compartments and on the …

Co-delivery strategy has been proposed to minimize the amount of each drug and to
achieve the synergistic effect for cancer therapies. A conjugate of the antitumor drug …

The surface functionalization of nanoporous silica materials with chemical agents opens up
numerous possibilities, including improvement in the materials' ability to carry high payloads …