[HTML][HTML] Current trends in pharmaceutical treatment of dry eye disease: A review
Dry eye disease (DED), keratoconjunctivitis sicca or dysfunctional tear syndrome, is the most
prevalent ophthalmic disease which affects a substantial segment of people worldwide with …
prevalent ophthalmic disease which affects a substantial segment of people worldwide with …
[HTML][HTML] Novel drug delivery systems for the management of dry eye
Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …
considerable research interest. Conventional therapy for DED involves the use of artificial …
[HTML][HTML] Formulation considerations for the management of dry eye disease
Dry eye disease (DED) is one of the most common ocular surface disorders characterised by
a deficiency in quality and/or quantity of the tear fluid. Due to its multifactorial nature …
a deficiency in quality and/or quantity of the tear fluid. Due to its multifactorial nature …
[HTML][HTML] Cyclodextrin stabilized freeze-dried silica/chitosan nanoparticles for improved terconazole ocular bioavailability
This research assesses the beneficial effects of loading terconazole, a poorly water-soluble
antifungal drug in silica/chitosan nanoparticles (SCNs) for ocular delivery. Nanoparticles …
antifungal drug in silica/chitosan nanoparticles (SCNs) for ocular delivery. Nanoparticles …
[HTML][HTML] Novel eye drop delivery systems: advance on formulation design strategies targeting anterior and posterior segments of the eye
Y Wang, C Wang - Pharmaceutics, 2022 - mdpi.com
Eye drops are the most common and convenient route of topical administration and the first
choice of treatment for many ocular diseases. However, the ocular bioavailability of …
choice of treatment for many ocular diseases. However, the ocular bioavailability of …
[HTML][HTML] Development and characterization of a tacrolimus/hydroxypropyl-β-cyclodextrin eye drop
X García-Otero, V Díaz-Tomé, R Varela-Fernández… - Pharmaceutics, 2021 - mdpi.com
Uveitis is a vision inflammatory disorder with a high prevalence in developing countries.
Currently, marketed treatments remain limited and reformulation is usually performed to …
Currently, marketed treatments remain limited and reformulation is usually performed to …
Drug-like properties and topical delivery of rapalogs and tacrolimus in ophthalmology
Rapalogs, including sirolimus and everolimus, as well as tacrolimus, are macrolide
immunosuppressants that have emerged as promising therapeutic agents in ophthalmology …
immunosuppressants that have emerged as promising therapeutic agents in ophthalmology …
Research progress of ophthalmic preparations of immunosuppressants
Y Liu, H Xu, N Yan, Z Tang, Q Wang - Drug Delivery, 2023 - Taylor & Francis
Immune ophthalmopathy is a collection of autoimmune eye diseases. Immunosuppressants
are drugs that can inhibit the body's immune response. Considering drug side effects such …
are drugs that can inhibit the body's immune response. Considering drug side effects such …
Cyclodextrin‐based nanosponges as promising carriers for active pharmaceutical ingredient
S Jawaharlal, S Subramanian… - … of Biochemical and …, 2024 - Wiley Online Library
Effective drug distribution at the intended or particular location is a critical issue that
researchers are now dealing. Nanosponges have significantly increased in importance in …
researchers are now dealing. Nanosponges have significantly increased in importance in …
Difluprednate-hydroxypropyl-β-cyclodextrin-based ophthalmic solution for improved delivery in a porcine eye model
Purpose: Difluprednate (DFP) is an approved corticosteroid, available as an ophthalmic
emulsion (Durezol®), used to treat pain and inflammation of the eye following ocular …
emulsion (Durezol®), used to treat pain and inflammation of the eye following ocular …