Prognostic and predictive biomarkers in gliomas

P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021 - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

The role of proteoglycans in cancer metastasis and circulating tumor cell analysis

TD Ahrens, SR Bang-Christensen… - Frontiers in cell and …, 2020 - frontiersin.org
Circulating tumor cells (CTCs) are accessible by liquid biopsies via an easy blood draw.
They represent not only the primary tumor site, but also potential metastatic lesions, and …

Detection and clinical significance of circulating tumor cells in colorectal cancer

M Jiang, S Jin, J Han, T Li, J Shi, Q Zhong, W Li… - Biomarker …, 2021 - Springer
Histopathological examination (biopsy) is the “gold standard” for the diagnosis of colorectal
cancer (CRC). However, biopsy is an invasive method, and due to the temporal and spatial …

Circulating tumor cells as predictive and prognostic biomarkers in solid tumors

M Capuozzo, F Ferrara, M Santorsola, A Zovi… - Cells, 2023 - mdpi.com
Circulating tumor cells (CTCs) have emerged as pivotal biomarkers with significant
predictive and prognostic implications in solid tumors. Their presence in peripheral blood …

Liquid biopsy: creating opportunities in brain space

R Trivedi, KP Bhat - British journal of cancer, 2023 - nature.com
In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Preoperative diagnosis and molecular characterization of gliomas with liquid biopsy and radiogenomics

C Balana, S Castañer, C Carrato, T Moran… - Frontiers in …, 2022 - frontiersin.org
Gliomas are a heterogenous group of central nervous system tumors with different outcomes
and different therapeutic needs. Glioblastoma, the most common subtype in adults, has a …

Blood-based biomarkers for glioma in the context of gliomagenesis: a systematic review

H Ali, R Harting, R de Vries, M Ali, T Wurdinger… - Frontiers in …, 2021 - frontiersin.org
Background Gliomas are the most common and aggressive tumors of the central nervous
system. A robust and widely used blood-based biomarker for glioma has not yet been …

Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection

PF Zhang, ZY Wu, WB Zhang, YQ He, K Chen… - Nature …, 2023 - nature.com
Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been
tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively …

Syndecan-4 as a pathogenesis factor and therapeutic target in cancer

JOS Onyeisi, CC Lopes, M Götte - Biomolecules, 2021 - mdpi.com
Cancer is an important cause of morbidity and mortality worldwide. Advances in research on
the biology of cancer revealed alterations in several key pathways underlying tumorigenesis …

Profiling of circulating glial cells for accurate blood‐based diagnosis of glial malignancies

K O'Neill, N Syed, T Crook, S Dubey… - … Journal of Cancer, 2024 - Wiley Online Library
Here, we describe a blood test for the detection of glial malignancies (GLI‐M) based on the
identification of circulating glial cells (CGCs). The test is highly specific for GLI‐M and can …