Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
WB Dunn, DI Broadhurst, HJ Atherton… - Chemical society …, 2011 - pubs.rsc.org
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
Chemometrics in metabolomics—a review in human disease diagnosis
R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
[HTML][HTML] In-cell NMR: Why and how?
FX Theillet, E Luchinat - Progress in Nuclear Magnetic Resonance …, 2022 - Elsevier
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …
[HTML][HTML] Triple-negative breast cancer: present challenges and new perspectives
F Podo, LMC Buydens, H Degani, R Hilhorst, E Klipp… - Molecular …, 2010 - Elsevier
Triple-negative breast cancers (TNBC), characterized by absence of estrogen receptor (ER),
progesterone receptor (PR) and lack of overexpression of human epidermal growth factor …
progesterone receptor (PR) and lack of overexpression of human epidermal growth factor …
Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine
In this study, 1H NMR-based metabonomics has been applied, for the first time to our
knowledge, to investigate lung cancer metabolic signatures in urine, aiming at assessing the …
knowledge, to investigate lung cancer metabolic signatures in urine, aiming at assessing the …
Metabolomics as a tool for the comprehensive understanding of fermented and functional foods with lactic acid bacteria
F Mozzi, ME Ortiz, J Bleckwedel, L De Vuyst… - Food Research …, 2013 - Elsevier
Metabolomics, also called metabonomics or metabolic profiling, deals with the simultaneous
determination and quantitative analysis of intracellular metabolites or low-molecular-mass …
determination and quantitative analysis of intracellular metabolites or low-molecular-mass …
Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of blood plasma
In this work, the variations in the metabolic profile of blood plasma from lung cancer patients
and healthy controls were investigated through NMR-based metabonomics, to assess the …
and healthy controls were investigated through NMR-based metabonomics, to assess the …
[HTML][HTML] Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide
MH Kulke, T O'Dorisio, A Phan… - Endocrine-Related …, 2014 - erc.bioscientifica.com
In this study, we i) assessed the metabolic profile of the normal adrenal cortex and medulla
of adult human subjects by means of 1 H-high-resolution magic-angle spinning nuclear …
of adult human subjects by means of 1 H-high-resolution magic-angle spinning nuclear …
A serum nuclear magnetic resonance-based metabolomic signature of advanced metastatic human breast cancer
E Jobard, C Pontoizeau, BJ Blaise, T Bachelot… - Cancer letters, 2014 - Elsevier
Breast cancer (BC) displays a high heterogeneity from histology to prognosis, metastatic
evolution and treatment responses. We report here a 1 H NMR-based metabolic …
evolution and treatment responses. We report here a 1 H NMR-based metabolic …
Metabolic Profiling of Human Lung Cancer Tissue by 1H High Resolution Magic Angle Spinning (HRMAS) NMR Spectroscopy
This work aims at characterizing the metabolic profile of human lung cancer, to gain new
insights into tumor metabolism and to identify possible biomarkers with potential diagnostic …
insights into tumor metabolism and to identify possible biomarkers with potential diagnostic …