Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …

By its strategic position at the interface between blood and tissues, endothelial cells control
blood fluidity and continued tissue perfusion while simultaneously they direct inflammatory …

Reversing brain aging may be possible through systemic interventions such as exercise. We
found that administration of circulating blood factors in plasma from exercised aged mice …

Valid experimental evidence has recently shown that progression of malignant tumors does
not depend exclusively on cell-autonomous properties of the cancer cells, but is also deeply …

Several recent papers have now provided compelling experimental evidence that the
progression of tumours towards a malignant phenotype does not depend exclusively on the …

Tumor microenvironment has emerged as an important target for cancer therapy. In
particular, cancer-associated fibroblasts (CAF) seem to regulate many aspects of …

D-dimer is the smallest fibrinolysis-specific degradation product found in the circulation. The
origins, assays, and clinical use of D-dimer will be addressed. Hemostasis (platelet and …

Prostate cancer (PCa) metabolism appears to be unique in comparison with other types of
solid cancers. Normal prostate cells mainly rely on glucose oxidation to provide precursors …

Oral Tongue Squamous cell carcinoma (OTSCC), the most frequently affected oral cancer
sub-site, is associated with a poor therapeutic outcome and survival despite aggressive …

Studies of epithelial cancers (ie, carcinomas) traditionally focused on transformation of the
epithelium (ie, the cancer cells) and how aberrant signaling within the cancer cells …