Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for developing or repurposing effective …

Pathological substance use disorders represent a major public health crisis with limited
effective treatment options. While much work has been done to understand the neuronal …

In recent years, some new processes have been proposed to explain how alcohol may
influence behavior, psychological symptoms and alcohol seeking in alcohol-dependent …

While the immune system is essential for survival, an excessive or prolonged inflammatory
response, such as that resulting from sustained heavy alcohol use, can damage the host …

Alcohol dependence and alcoholic liver disease represent a major public health problem
with substantial morbidity and mortality. By yet incompletely understood mechanisms …

Background The plenary session at the 2016 Behavior, Biology and Chemistry:
Translational Research in Addiction Conference focused on glia as potential players in the …

Neuroinflammation is a complex process involved in the physiophatology of many central
nervous system diseases, including addiction. Alcohol abuse is characterized by induction …

There is accumulating evidence that alcohol consumption and especially alcohol withdrawal
increase brain levels of known innate immune signaling molecules and cause …

Cocaine addiction is a chronic relapsing disorder characterized by persistent perturbations
to an organism's homeostatic processes that result in maladaptive drug seeking. Although …

Excessive alcohol use disrupts neuroimmune signaling across various cell types, including
neurons, microglia, and astrocytes. The present review focuses on recent, albeit limited …