PI3K/Akt signaling in osteosarcoma

J Zhang, XH Yu, YG Yan, C Wang, WJ Wang - Clinica chimica acta, 2015 - Elsevier
Osteosarcoma (OS) is the most common nonhematologic bone malignancy in children and
adolescents. Despite the advances of adjuvant chemotherapy and significant improvement …

Early detection of lung cancer biomarkers through biosensor technology: A review

A Roointan, TA Mir, SI Wani, KK Hussain… - … of pharmaceutical and …, 2019 - Elsevier
Lung cancer is undoubtedly one of the most serious health issues of the 21 st century. It is
the second leading cause of cancer-related deaths in both men and women worldwide …

MicroRNA in lung cancer: novel biomarkers and potential tools for treatment

K Inamura, Y Ishikawa - Journal of clinical medicine, 2016 - mdpi.com
Lung cancer is the leading cause of cancer death in men and women worldwide. The lack of
specific and sensitive tools for early diagnosis as well as still-inadequate targeted therapies …

MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer

DI Chen, W Guo, Z Qiu, Q Wang, Y Li, L Liang, L Liu… - Cancer letters, 2015 - Elsevier
MicroRNAs (miRNAs) are small, single-stranded, non-coding RNA molecules that are
dysregulated in many types of human cancers, although their precise functions in driving …

Considering exosomal miR-21 as a biomarker for cancer

J Shi - Journal of clinical medicine, 2016 - mdpi.com
Cancer is a fatal human disease. Early diagnosis of cancer is the most effective method to
prevent cancer development and to achieve higher survival rates for patients. Many …

[HTML][HTML] Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages

Y Teng, J Mu, X Hu, A Samykutty, X Zhuang, Z Deng… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Liver metastasis accounts for many of the cancer deaths in patients. Effective treatment for
metastatic liver tumors is not available. Here, we provide evidence for the role of miR-18a in …

Role of miRNA in lung cancer-potential biomarkers and therapies

X Du, J Zhang, J Wang, X Lin… - Current pharmaceutical …, 2017 - ingentaconnect.com
MicroRNAs (miRNAs) are small noncoding RNAs, which downregulate gene expression by
repressing or degrading mRNA targets. Lung cancer (LC), together with liver and colorectal …

[HTML][HTML] Early detection of lung cancer

DE Midthun - F1000Research, 2016 - ncbi.nlm.nih.gov
Most patients with lung cancer are diagnosed when they present with symptoms, they have
advanced stage disease, and curative treatment is no longer an option. An effective …

Early epigenetic markers for precision medicine

RG Dumitrescu - Cancer Epigenetics for Precision Medicine: Methods …, 2018 - Springer
Over the last years, epigenetic changes, including DNA methylation and histone
modifications detected in early tumorigenesis and cancer progression, have been proposed …

[HTML][HTML] MicroRNA in pancreatic adenocarcinoma: predictive/prognostic biomarkers or therapeutic targets?

O Brunetti, A Russo, A Scarpa, D Santini, M Reni… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a tumor with a poor prognosis, short overall
survival and few chemotherapeutic choices. MicroRNAs (miRNAs) are non-coding, single …