Zebrafish have several advantages compared to other vertebrate models used in modeling
human diseases, particularly for large-scale genetic mutant and therapeutic compound …

This review is aimed to provide a concise yet extensive survey of key short bioactive peptide
sequences for a range of applications ranging from biomaterials development to peptides …

Dysregulation of peptide-activated pathways causes a range of diseases, fostering the
discovery and clinical development of peptide drugs. Many endogenous peptides activate G …

Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

The precise orchestration of hormonal regulation at all levels of the hypothalamic-pituitary-
gonadal axis is essential for normal reproductive function and fertility. The pulsatile secretion …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …

Life stress is a central construct in health research because it is associated with increased
risk for a variety of serious mental and physical health problems, including anxiety disorders …

Teleosts lack a hypophyseal portal system and hence neurohormones are carried by nerve
fibers from the preoptic region to the pituitary. The various cell types in the teleost pituitary …

BACKGROUND Human reproduction depends on an intact hypothalamic–pituitary–gonadal
(HPG) axis. Hypothalamic gonadotrophin-releasing hormone (GnRH) has been recognized …