Recent progresses in the field of Induced Pluripotent Stem Cells (iPSCs) have opened up
many gateways for the research in therapeutics. iPSCs are the cells which are …

Astrocytes have a central role in brain development and function, and so have gained
increasing attention over the past two decades. Consequently, our knowledge about their …

Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disorder. Although its
neuropathology is well understood, the cellular and molecular mechanisms are yet to be …

With the help of several inducing factors, somatic cells can be reprogrammed to become
induced pluripotent stem cell (iPSCs) lines. The success is in obtaining iPSCs almost …

Huntington's disease (HD) is a severe autosomal-dominant neurodegenerative disorder
caused by a mutation within a gene, encoding huntingtin protein. Here we have used the …

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that leads to
widespread motor neuron death, general palsy and respiratory failure. The most prevalent …

The ability to reprogram adult somatic cells into pluripotent stem cells that can differentiate
into all three germ layers of the developing human has fundamentally changed the …

Induced pluripotent stem (iPS) cells were created from mouse fibroblasts by induced
expression of Yamanaka factors, Oct3/4, Sox2, Klf4, and c-Myc. This technique has quickly …

Amyotrophic lateral sclerosis (ALS) is a progressive, noncurable neurodegenerative
disorder of the upper and lower motor neurons causing weakness and death within a few …

Stem cell is defined by its ability to self-renewal and generates differentiated functional cell
types, which are derived from the embryo and various sources of postnatal animal. These …