Production of gamma-aminobutyric acid from lactic acid bacteria: A systematic review

Y Cui, K Miao, S Niyaphorn, X Qu - International Journal of Molecular …, 2020 - mdpi.com
Gamma-aminobutyric acid (GABA) is widely distributed in nature and considered a potent
bioactive compound with numerous and important physiological functions, such as anti …

Glutamate decarboxylase from lactic acid bacteria—A key enzyme in GABA synthesis

IBA Yogeswara, S Maneerat, D Haltrich - Microorganisms, 2020 - mdpi.com
Glutamate decarboxylase (l-glutamate-1-carboxylase, GAD; EC 4.1. 1.15) is a pyridoxal-5'-
phosphate-dependent enzyme that catalyzes the irreversible α-decarboxylation of l-glutamic …

GABA production and structure of gadB/gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota

RA Yunes, EU Poluektova, MS Dyachkova, KM Klimina… - Anaerobe, 2016 - Elsevier
Gamma-amino butyric acid (GABA) is an active biogenic substance synthesized in plants,
fungi, vertebrate animals and bacteria. Lactic acid bacteria are considered the main …

Some important metabolites produced by lactic acid bacteria originated from kimchi

SJ Lee, HS Jeon, JY Yoo, JH Kim - Foods, 2021 - mdpi.com
Lactic acid bacteria (LAB) have been used for various food fermentations for thousands of
years. Recently, LAB are receiving increased attention due to their great potential as …

High γ-aminobutyric acid production from lactic acid bacteria: Emphasis on Lactobacillus brevis as a functional dairy starter

Q Wu, NP Shah - Critical Reviews in Food Science and Nutrition, 2017 - Taylor & Francis
ABSTRACT γ-Aminobutyric acid (GABA) and GABA-rich foods have shown anti-
hypertensive and anti-depressant activities as the major functions in humans and animals …

Glutamate decarboxylase‐dependent acid resistance in orally acquired bacteria: function, distribution and biomedical implications of the gadBC operon

D De Biase, E Pennacchietti - Molecular microbiology, 2012 - Wiley Online Library
For successful colonization of the mammalian host, orally acquired bacteria must overcome
the extreme acidic stress (pH< 2.5) encountered during transit through the host stomach …

Microbial Production and Enzymatic Biosynthesis of γ-Aminobutyric Acid (GABA) Using Lactobacillus plantarum FNCC 260 Isolated from Indonesian Fermented …

IBA Yogeswara, S Kittibunchakul, ES Rahayu… - Processes, 2020 - mdpi.com
In the present study, we isolated and screened thirty strains of GABA (γ-aminobutyric acid)-
producing lactic acid bacteria (LAB) from traditional Indonesian fermented foods. Two strains …

[HTML][HTML] Evaluation of improved γ-aminobutyric acid production in yogurt using Lactobacillus plantarum NDC75017

Y Shan, CX Man, X Han, L Li, Y Guo, Y Deng, T Li… - Journal of dairy …, 2015 - Elsevier
Most γ-aminobutyric acid (GABA)-producing microorganisms are lactic acid bacteria (LAB),
but the yield of GABA is limited in most of these GABA-producing strains. In this study, the …

Screening Potential Probiotic Characteristics of Lactobacillus brevis Strains In Vitro and Intervention Effect on Type I Diabetes In Vivo

A Abdelazez, H Abdelmotaal, SE Evivie… - BioMed Research …, 2018 - Wiley Online Library
Diabetes has become the third most serious threat to human health, after cancer and
cardiovascular disease. Notably, Lactobacillus brevis is the most common species of LAB …

Common Distribution of gad Operon in Lactobacillus brevis and its GadA Contributes to Efficient GABA Synthesis toward Cytosolic Near-Neutral pH

Q Wu, HM Tun, YS Law, E Khafipour… - Frontiers in …, 2017 - frontiersin.org
Many strains of lactic acid bacteria (LAB) and bifidobacteria have exhibited strain-specific
capacity to produce γ-aminobutyric acid (GABA) via their glutamic acid decarboxylase (GAD) …