Objective To evaluate the peer-reviewed literature on hypothyroidism, hyperthyroidism, and
thyroid autoimmunity in pregnancy. Methods We review published studies on thyroid …

In pregnancy, several physiological changes affect maternal circulating thyroid hormone
levels. The most common causes of hyperthyroidism in pregnancy are Graves' disease and …

Objective Maternal hyperthyroidism and antithyroid medications have been associated with
adverse pregnancy and perinatal outcomes. This nationwide register‐based study …

The early identification of teratogens in humans and animals is mandatory for drug discovery
and development. Zebrafish has emerged as an alternative model to traditional preclinical …

Purpose Control of thyroid function in hyperthyroid women during pregnancy is based on
antithyroid drugs (ATD)[propylthiouracil (PTU) and methimazole (MMI)]. While a teratogenic …

Drug intake in pregnant women is common, including prescribed and over-the-counter
medications, and herbal medicine and supplements. Drug-induced liver injury (DILI) has …

To understand the effect of fetal thyroid gland disruption on development in swine, we
evaluated thyroid hormone levels, growth and developmental characteristics, and gene …

Thyroid hormones are essential developmental factors, and Graves' disease (GD) may
severely complicate a pregnancy. This review describes how pregnancy changes the risk of …

Maternal hyperthyroidism is associated with an increased incidence of congenital
abnormalities at birth, but it is not clear which of these defects arise from a transient …

Maternal hypothyroidism (MH) is the most common cause of transient congenital
hypothyroidism. Different animal models are used for assessing developmental effects of …