[HTML][HTML] Aging unconventionally: γδ T cells, iNKT cells, and MAIT cells in aging

A Kurioka, P Klenerman - Seminars in Immunology, 2023 - Elsevier
Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …

From snoot to tail: a brief review of influenza virus infection and immunity in pigs

W Ma, CL Loving, JP Driver - The Journal of Immunology, 2023 - journals.aai.org
Pigs play an important role in influenza A virus (IAV) epidemiology because they support
replication of human, avian, and swine origin viruses and act as an IAV reservoir for pigs …

Local and systemic T cell immunity in fighting pig viral and bacterial infections

W Gerner, KH Mair, S Schmidt - Annual Review of Animal …, 2022 - annualreviews.org
T cells are an essential component of the adaptive immune system. Over the last 15 years, a
constantly growing toolbox with which to study T cell biology in pigs has allowed detailed …

[HTML][HTML] A single-cell analysis of thymopoiesis and thymic iNKT cell development in pigs

W Gu, DMC Madrid, S Joyce, JP Driver - Cell reports, 2022 - cell.com
Many aspects of the porcine immune system remain poorly characterized, which poses a
barrier to improving swine health and utilizing pigs as preclinical models. Here, we employ …

γδ T cells in artiodactyls: Focus on swine

L Le Page, CL Baldwin, JC Telfer - Developmental & Comparative …, 2022 - Elsevier
Vaccination is the most effective medical strategy for disease prevention but there is a need
to improve livestock vaccine efficacy. Understanding the structure of the immune system of …

Genomic and comparative analysis of the T cell receptor gamma locus in two Equus species

S Massari, F Giannico, NV Paolillo, A Pala… - Frontiers in …, 2023 - frontiersin.org
The genus Equus is the only extant genus of the Equidae family, which belongs to
Perissodactyla, an order of mammals characterized by an odd number of toes (odd-toes …

Genetic architecture of innate and adaptive immune cells in pigs

M Ballester, T Jové-Juncà, A Pascual… - Frontiers in …, 2023 - frontiersin.org
Pig industry is facing new challenges that make necessary to reorient breeding programs to
produce more robust and resilient pig populations. The aim of the present work was to study …

A genome assembly and transcriptome atlas of the inbred Babraham pig to illuminate porcine immunogenetic variation

JC Schwartz, CP Farrell, G Freimanis, AK Sewell… - Immunogenetics, 2024 - Springer
The inbred Babraham pig serves as a valuable biomedical model for research due to its
high level of homozygosity, including in the major histocompatibility complex (MHC) loci and …

Progress in the development and use of monoclonal antibodies to study the evolution and function of the immune systems in the extant lineages of ungulates

WC Davis, AH Mahmoud, V Hulubei, A Hasan… - Veterinary Immunology …, 2024 - Elsevier
Details on the origin and function of the immune system are beginning to emerge from
genomic studies tracing the origin of B and T cells and the major histocompatibility complex …

Swine unconventional T cells

M Wu, Q Jiang, A Nazmi, J Yin, G Yang - Developmental & Comparative …, 2022 - Elsevier
Pigs are important domestic livestock and a comprehensive understanding of their immune
system is critical to improve swine vaccine efficacy. Pig models represent an excellent …