Linkage disequilibrium (LD) is a fundamental concept in genetics; critical for studying
genetic associations and molecular evolution. However, LD measurements are only reliable …

Genomic selection uses whole-genome marker models to predict phenotypes or genetic
values for complex traits. Some of these models fit interaction terms between markers, and …

Average effects of alleles can show considerable differences between populations. The
magnitude of these differences can be measured by the additive genetic correlation …

Background Autoimmune hepatitis has an unknown cause and genetic associations that are
not disease-specific or always present. Clarification of its missing causality and heritability …

It is natural to assume that patterns of genetic variation in hyperpolymorphic species can
reveal large-scale properties of the fitness landscape that are hard to detect by studying …

Key message We propose to use the natural variation between individuals of a population
for genome assembly scaffolding. In today's genome projects, multiple accessions get …

Detecting epistatic drivers of human phenotypes is a considerable challenge. Traditional
approaches use regression to sequentially test multiplicative interaction terms involving …

Gene–environment interaction is a key part of evolutionary biology, animal, and plant
breeding, and a number of health sciences, like epidemiology and precision medicine …

[en] Understanding the interplay between genomics and human health is a crucial step for
the advancement and development of our society. Genome-Wide Association Study (GWAS) …

The natural and orthogonal interactions (NOIA) model was originally developed not only as
one more step in the improvement of genetic models but actually as a sound basis for the …