p-Adic mathematical physics: the first 30 years
Abstract p-Adic mathematical physics is a branch of modern mathematical physics based on
the application of p-adic mathematical methods in modeling physical and related …
the application of p-adic mathematical methods in modeling physical and related …
Two independent modes of chromatin organization revealed by cohesin removal
Imaging and chromosome conformation capture studies have revealed several layers of
chromosome organization, including segregation into megabase-sized active and inactive …
chromosome organization, including segregation into megabase-sized active and inactive …
TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics
IR Mackenzie, AM Nicholson, M Sarkar, J Messing… - Neuron, 2017 - cell.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are age-related
neurodegenerative disorders with shared genetic etiologies and overlapping clinical and …
neurodegenerative disorders with shared genetic etiologies and overlapping clinical and …
Spatial organization of chromatin domains and compartments in single chromosomes
The spatial organization of chromatin critically affects genome function. Recent chromosome-
conformation-capture studies have revealed topologically associating domains (TADs) as a …
conformation-capture studies have revealed topologically associating domains (TADs) as a …
[HTML][HTML] Modeling chromosomes: Beyond pretty pictures
Abstract Recently, Chromosome Conformation Capture (3C) based experiments have
highlighted the importance of computational models for the study of chromosome …
highlighted the importance of computational models for the study of chromosome …
FISH-ing for captured contacts: towards reconciling FISH and 3C
G Fudenberg, M Imakaev - Nature methods, 2017 - nature.com
Chromosome conformation capture (3C) and fluorescence in situ hybridization (FISH) are
two widely used technologies that provide distinct readouts of 3D chromosome organization …
two widely used technologies that provide distinct readouts of 3D chromosome organization …
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection
Background CTCF is a key insulator-binding protein, and mammalian genomes contain
numerous CTCF sites, many of which are organized in tandem. Results Using CRISPR DNA …
numerous CTCF sites, many of which are organized in tandem. Results Using CRISPR DNA …
How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes
The 3D organization of chromosomes is crucial for regulating gene expression and cell
function. Many experimental and polymer modeling efforts are dedicated to deciphering the …
function. Many experimental and polymer modeling efforts are dedicated to deciphering the …
Self-Dual Criticality in Three-Dimensional Gauge Theory with Matter
The simplest topologically ordered phase in 2+ 1 D is the deconfined phase of Z 2 gauge
theory (realized in the toric code, for example). This phase permits a duality that exchanges …
theory (realized in the toric code, for example). This phase permits a duality that exchanges …
Anomalous diffusion in fractal globules
The fractal globule state is a popular model for describing chromatin packing in eukaryotic
nuclei. Here we provide a scaling theory and dissipative particle dynamics computer …
nuclei. Here we provide a scaling theory and dissipative particle dynamics computer …