Antifungal resistance in dermatophytes: Recent trends and therapeutic implications

A Khurana, K Sardana, A Chowdhary - Fungal Genetics and Biology, 2019 - Elsevier
Dermatophytoses or tinea refers to superficial fungal infection of keratinized tissues.
Although generally considered easy to treat, recalcitrant infections, presenting as extensive …

Major challenges and perspectives in the diagnostics and treatment of dermatophyte infections

S Gnat, D Łagowski… - Journal of applied …, 2020 - academic.oup.com
Dermatophytes are the aetiological factors of a majority of superficial fungal infections. What
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …

Dermatophyte resistance to antifungal drugs: mechanisms and prospectus

NM Martinez-Rossi, TA Bitencourt, NTA Peres… - Frontiers in …, 2018 - frontiersin.org
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …

State-of-the-art dermatophyte infections: epidemiology aspects, pathophysiology, and resistance mechanisms

NM Martinez-Rossi, NTA Peres, TA Bitencourt… - Journal of Fungi, 2021 - mdpi.com
The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …

Skin immunity to dermatophytes: From experimental infection models to human disease

VL Burstein, I Beccacece, L Guasconi… - Frontiers in …, 2020 - frontiersin.org
Dermatophytoses (ringworms) are among the most frequent skin infections and are a highly
prevalent cause of human disease worldwide. Despite the incidence of these superficial …

Pathogenesis of dermatophytosis: sensing the host tissue

NM Martinez-Rossi, NTA Peres, A Rossi - Mycopathologia, 2017 - Springer
Abstract The genera Trichophyton, Microsporum, and Epidermophyton include filamentous
fungi that cause dermatophytosis, a superficial infection of the skin, stratum corneum, nail …

Host-and pathogen-dependent susceptibility and predisposition to dermatophytosis

S Gnat, A Nowakiewicz… - Journal of medical …, 2019 - microbiologyresearch.org
Dermatophytes are a highly specialized group of keratinophilic and keratinolytic filamentous
fungi causing a ringworm disease called dermatophytosis or superficial mycoses. Although …

An update on the myriad antifungal resistance mechanisms in dermatophytes and the place of experimental and existential therapeutic agents for Trichophyton …

K Sardana, S Sharath, A Khurana… - Expert Review of Anti …, 2023 - Taylor & Francis
Introduction There is an epidemic emergence of increased resistance in dermatophytes with
to antifungal drugs with ergosterol1 (Erg1) and Erg11 mutations to terbinafine and azoles …

Disrupting effects of antibiotic sulfathiazole on developmental process during sensitive life-cycle stage of Chironomus riparius

K Park, IS Kwak - Chemosphere, 2018 - Elsevier
Antibiotics in the environment are a concern due to their potential to harm humans and
interrupt ecosystems. Sulfathiazole (STZ), a sulfonamide antibiotic, is commonly used in …

Dermatophyte infection: from fungal pathogenicity to host immune responses

R Deng, X Wang, R Li - Frontiers in Immunology, 2023 - frontiersin.org
Dermatophytosis is a common superficial infection caused by dermatophytes, a group of
pathogenic keratinophilic fungi. Apart from invasion against skin barrier, host immune …