Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE

HB Nguyen, AK Jaehne, N Jayaprakash, MW Semler… - Critical Care, 2016 - Springer
Prior to 2001 there was no standard for early management of severe sepsis and septic
shock in the emergency department. In the presence of standard or usual care, the …

Severe sepsis and septic shock: review of the literature and emergency department management guidelines

HB Nguyen, EP Rivers, FM Abrahamian… - Annals of emergency …, 2006 - Elsevier
Severe sepsis and septic shock are as common and lethal as other acute life-threatening
conditions that emergency physicians routinely confront such as acute myocardial infarction …

[图书][B] Medical biostatistics

A Indrayan, RK Malhotra - 2017 - taylorfrancis.com
Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Fourth Edition
focuses on the statistical aspects ofmedicine with a medical perspective, showing the utility …

ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation

CF de Oliveira, DSF de Oliveira, AFC Gottschald… - Intensive care …, 2008 - Springer
Abstract Introduction The ACCM/PALS guidelines address early correction of paediatric
septic shock using conventional measures. In the evolution of these recommendations …

Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning …

NI Lone, TS Walsh - Critical Care, 2011 - Springer
Introduction The number of patients requiring prolonged mechanical ventilation (PMV) is
likely to increase. Transferring patients to specialised weaning units may improve outcomes …

Early goal-directed therapy in severe sepsis and septic shock revisited: concepts, controversies, and contemporary findings

RM Otero, HB Nguyen, DT Huang, DF Gaieski, M Goyal… - Chest, 2006 - Elsevier
Studies of acute myocardial infarction, trauma, and stroke have been translated into
improved outcomes by earlier diagnosis and application of therapy at the most proximal …

Clinical characteristics and outcomes of obstetric patients requiring ICU admission

DN Vasquez, E Estenssoro, HS Canales, R Reina… - Chest, 2007 - Elsevier
Objectives: To review a series of critically ill obstetric patients admitted to our ICU to assess
the spectrum of disease, required interventions, and fetal/maternal mortality, and to identify …

Effect of acute kidney injury on weaning from mechanical ventilation in critically ill patients

JM Vieira Jr, I Castro, A Curvello-Neto… - Critical care …, 2007 - journals.lww.com
Objectives: Acute kidney injury (AKI) worsens outcome in various scenarios. We sought to
investigate whether the occurrence of AKI has any effect on weaning from mechanical …

Early and innovative interventions for severe sepsis and septic shock: taking advantage of a window of opportunity

EP Rivers, L McIntyre, DC Morro, KK Rivers - Cmaj, 2005 - Can Med Assoc
The pathogenic, diagnostic and therapeutic landscape of sepsis is no longer confined to the
intensive care unit: many patients from other portals of entry to care, both outside and within …

The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock

EP Rivers, JA Kruse, G Jacobsen, K Shah… - Critical care …, 2007 - journals.lww.com
Background: Despite abundant experimental studies of biomarker patterns in early severe
sepsis and septic shock, human data are few. Further, the impact of the severity of global …