Pulsed electromagnetic fields in bone healing: molecular pathways and clinical applications

L Caliogna, M Medetti, V Bina, AM Brancato… - International Journal of …, 2021 - mdpi.com
In this article, we provide an extensive review of the recent literature of the signaling
pathways modulated by Pulsed Electromagnetic Fields (PEMFs) and PEMFs clinical …

[HTML][HTML] Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review

F Hashemi-Afzal, H Fallahi, F Bagheri, MN Collins… - Bioactive Materials, 2025 - Elsevier
This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …

[HTML][HTML] Enhancing cartilage repair with optimized supramolecular hydrogel-based scaffold and pulsed electromagnetic field

Y Li, L Li, Y Li, L Feng, B Wang, M Wang, H Wang… - Bioactive Materials, 2023 - Elsevier
Functional tissue engineering strategies provide innovative approach for the repair and
regeneration of damaged cartilage. Hydrogel is widely used because it could provide rapid …

A review on external physical stimuli with biomaterials for bone repair

T Luo, B Tan, J Liao, K Shi, L Ning - Chemical Engineering Journal, 2024 - Elsevier
Bone repair is a complex process that involves the inflammatory response, angiogenesis,
and bone remodeling. The traditional bone defect treatment process suffers from a lack of …

Low intensity pulsed ultrasound for bone healing: systematic review of randomized controlled trials

S Schandelmaier, A Kaushal, L Lytvyn… - Bmj, 2017 - bmj.com
Objective To determine the efficacy of low intensity pulsed ultrasound (LIPUS) for healing of
fracture or osteotomy. Design Systematic review and meta-analysis. Data sources Medline …

Efficacy of electrical stimulators for bone healing: a meta-analysis of randomized sham-controlled trials

IS Aleem, I Aleem, N Evaniew, JW Busse… - Scientific reports, 2016 - nature.com
Electrical stimulation is a common adjunct used to promote bone healing; its efficacy,
however, remains uncertain. We conducted a meta-analysis of randomized sham-controlled …

Translational insights into extremely low frequency pulsed electromagnetic fields (ELF-PEMFs) for bone regeneration after trauma and orthopedic surgery

S Ehnert, S Schröter, RH Aspera-Werz, W Eisler… - Journal of clinical …, 2019 - mdpi.com
The finding that alterations in electrical potential play an important role in the mechanical
stimulation of the bone provoked hype that noninvasive extremely low frequency pulsed …

Electrical stimulation-based bone fracture treatment, if it works so well why do not more surgeons use it?

MB Bhavsar, Z Han, T DeCoster, L Leppik… - European Journal of …, 2020 - Springer
Abstract Background Electrical stimulation (EStim) has been proven to promote bone
healing in experimental settings and has been used clinically for many years and yet it has …

Effectiveness of pulsed electromagnetic fields on bone healing: A systematic review and meta‐analysis of randomized controlled trials

L Peng, C Fu, F Xiong, Q Zhang, Z Liang… - …, 2020 - Wiley Online Library
The effect of pulsed electromagnetic field (PEMF) on bone healing is still uncertain and it
has not been established as a standardized treatment. The aim of this systematic review and …

Pulsed electro-magnetic field (pemf) effect on bone healing in animal models: a review of its efficacy related to different type of damage

M Di Bartolomeo, F Cavani, A Pellacani, A Grande… - Biology, 2022 - mdpi.com
Simple Summary Pulsed electromagnetic fields (PEMFs) are a type of biophysical
stimulation that has been shown to be effective in improving bone regeneration and …