Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines

RJ Turesky, L Le Marchand - Chemical research in toxicology, 2011 - ACS Publications
Aromatic amines and heterocyclic aromatic amines (HAAs) are structurally related classes of
carcinogens that are formed during the combustion of tobacco or during the high …

Acrylamide formation and different mitigation strategies during food processing–a review

AA Maan, MA Anjum, MKI Khan, A Nazir… - Food Reviews …, 2022 - Taylor & Francis
Thermal treatment can initiate the production of some undesirable compounds in foods
during processing. Acrylamide is one among such compounds that is produced (in starch …

Orthopaedic metals and their potential toxicity in the arthroplasty patient: a review of current knowledge and future strategies

GM Keegan, ID Learmonth… - The Journal of Bone & …, 2007 - boneandjoint.org.uk
The long-term effects of metal-on-metal arthroplasty are currently under scrutiny because of
the potential biological effects of metal wear debris. This review summarises data describing …

Application of the Margin of Exposure (MOE) approach to substances in food that are genotoxic and carcinogenic

D Benford, PM Bolger, P Carthew, M Coulet… - Food and chemical …, 2010 - Elsevier
This paper presents the work of an expert group established by the International Life
Sciences Institute–European branch (ILSI Europe) to follow up the recommendations of an …

The challenge of global aflatoxins legislation with a focus on peanuts and peanut products: a systematic review

JP Meneely, O Kolawole, SA Haughey, SJ Miller… - Exposure and …, 2023 - Springer
Globally, of all mycotoxins, aflatoxins present a significant threat to human and animal health
and has resulted in the introduction of strict food regulatory limits to protect public health. A …

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

LG Hernández, H van Steeg, M Luijten… - … Research/Reviews in …, 2009 - Elsevier
It is well established that cancer is a multi-step process which involves initiation, promotion
and progression. Chemical carcinogens can alter any of these processes to induce their …

[HTML][HTML] The role of hazard-and risk-based approaches in ensuring food safety

SM Barlow, AR Boobis, J Bridges, A Cockburn… - Trends in Food Science …, 2015 - Elsevier
Background Food legislation in the European Union and elsewhere includes both hazard-
and risk-based approaches for ensuring safety. In hazard-based approaches, simply the …

Risk assessment of mixtures of pesticides. Current approaches and future strategies

TK Reffstrup, JC Larsen, O Meyer - Regulatory toxicology and …, 2010 - Elsevier
The risk assessment of pesticide residues in food is based on toxicological evaluation of the
single compounds and no internationally accepted procedure exists for evaluation of …

Human skin penetration of selected model mycotoxins

J Boonen, SV Malysheva, L Taevernier… - Toxicology, 2012 - Elsevier
Dermal exposure data for mycotoxins are very scarce and fragmentary, despite their
widespread skin contact and hazard toxicity. In this study, the transdermal kinetics of …

Contamination levels in recollected PET bottles from non-food applications and their impact on the safety of recycled PET for food contact

R Franz, F Welle - Molecules, 2020 - mdpi.com
PET beverage bottles have been recycled and safely reprocessed into new food contact
packaging applications for over two decades. During recollection of post-consumer PET …