Endometriosis is a chronic and debilitating condition affecting∼ 10% of women.
Endometriosis is characterized by infertility and chronic pelvic pain, yet treatment options …

BACKGROUND Many clinicians and patients believe that endometriosis-associated pain is
due to the lesions. Yet causality remains an enigma, because pain symptoms attributed to …

Chronic pelvic pain is a frustrating symptom for patients with endometriosis and is frequently
refractory to hormonal and surgical management. While these therapies target ectopic …

Endometriosis is an estrogen-dependent gynecological disorder, defined as the growth of
endometrial stromal cells and glands at extrauterine sites. Endometriotic lesions are more …

Endometriosis is an extremely prevalent estrogen-dependent condition characterized by the
growth of ectopic endometrial tissue outside the uterine cavity, and is often presented with …

Although pain is one of the main symptoms women with endometriosis present with, there is
poor correlation between symptom severity and disease burden and the underlying …

Endometriosis is a chronic inflammatory disease. Pain is the most common symptom in
endometriosis. Endometriosis-associated pain is caused by inflammation, and is related to …

BACKGROUND Pain remains the cardinal symptom of endometriosis. However, to date, the
underlying mechanisms are still only poorly understood. Increasing evidence points towards …

Dysregulation of the immune system in endometriotic milieus has been considered to play a
pivotal role in the pathogenesis of endometriosis. Macrophage recruitment and nerve fiber …

Endometriosis is a chronic, hormone-dependent, inflammatory disease, characterized by the
presence and growth of endometrial tissue outside the uterine cavity. It affects 5–10% of the …