How far have we explored fungi to fight cancer?
The use of fungal cultures have been well documented in human history. Although its used
in healthcare, like penicillin and statins, have saved countless of lives, but there is still no …
in healthcare, like penicillin and statins, have saved countless of lives, but there is still no …
Hepatitis B virus (HBV) subviral particles as protective vaccines and vaccine platforms
JKT Ho, B Jeevan-Raj, HJ Netter - Viruses, 2020 - mdpi.com
Hepatitis B remains one of the major global health problems more than 40 years after the
identification of human hepatitis B virus (HBV) as the causative agent. A critical turning point …
identification of human hepatitis B virus (HBV) as the causative agent. A critical turning point …
Yeast-based virus-like particles as an emerging platform for vaccine development and delivery
Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
Recent advances in the production of recombinant subunit vaccines in Pichia pastoris
M Wang, S Jiang, Y Wang - Bioengineered, 2016 - Taylor & Francis
Recombinant protein subunit vaccines are formulated using defined protein antigens that
can be produced in heterologous expression systems. The methylotrophic yeast Pichia …
can be produced in heterologous expression systems. The methylotrophic yeast Pichia …
Pichia pastoris (Komagataella phaffii) as a Cost-Effective Tool for Vaccine Production for Low- and Middle-Income Countries (LMICs)
S de Sá Magalhães, E Keshavarz-Moore - Bioengineering, 2021 - mdpi.com
Vaccination is of paramount importance to global health. With the advent of the more recent
pandemics, the urgency to expand the range has become even more evident. However, the …
pandemics, the urgency to expand the range has become even more evident. However, the …
Recombinant protein subunit vaccine synthesis in microbes: a role for yeast?
RM Bill - Journal of Pharmacy and Pharmacology, 2015 - academic.oup.com
Objectives Recombinant protein subunit vaccines are formulated using protein antigens that
have been synthesized in heterologous host cells. Several host cells are available for this …
have been synthesized in heterologous host cells. Several host cells are available for this …
Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules
I Legastelois, S Buffin, I Peubez, C Mignon… - Human vaccines & …, 2017 - Taylor & Francis
The increasing demand for recombinant vaccine antigens or immunotherapeutic molecules
calls into question the universality of current protein expression systems. Vaccine production …
calls into question the universality of current protein expression systems. Vaccine production …
Multiplexed quantitative proteomic analysis of HEK293 provides insights into molecular changes associated with the cell density effect, transient transfection, and virus …
J Lavado-García, I Jorge, L Cervera… - Journal of proteome …, 2020 - ACS Publications
The production of virus-like particles (VLPs) has gained importance over the last few years
owing to the benefits they provide compared to conventional vaccines. The …
owing to the benefits they provide compared to conventional vaccines. The …
[PDF][PDF] Pichia pastoris expression system: a potential candidate to express protein in industrial and biopharmaceutical domains
The methylotrophic yeast Pichia pastoris is a widely used, well established protein
expression system for the production of biopharmaceutical and industrial enzymes. It is by …
expression system for the production of biopharmaceutical and industrial enzymes. It is by …
Selective extraction of recombinant membrane proteins from Hansenula polymorpha by pulsed electric field and lytic enzyme pretreatment
V Ganeva, A Kranz - Microbial Cell Factories, 2023 - Springer
Background In yeast, recombinant membrane proteins including viral scaffold proteins used
for the formation of enveloped Virus-like particles (eVLPs) typically accumulate …
for the formation of enveloped Virus-like particles (eVLPs) typically accumulate …