A review of bioactive compounds against porcine enteric coronaviruses

C Duan, Y Luo, X Liang, X Wang - Viruses, 2022 - mdpi.com
Pig diarrhea is a universal problem in the process of pig breeding, which seriously affects
the development of the pig industry. Porcine enteric coronaviruses (PECoVs) are common …

Coronavirus porcine epidemic diarrhea virus nucleocapsid protein interacts with p53 to induce cell cycle arrest in S-phase and promotes viral replication

M Su, D Shi, X Xing, S Qi, D Yang, J Zhang… - Journal of …, 2021 - Am Soc Microbiol
Subversion of the host cell cycle to facilitate viral replication is a common feature of
coronavirus infections. Coronavirus nucleocapsid (N) protein can modulate the host cell …

Tomatidine inhibits porcine epidemic diarrhea virus replication by targeting 3CL protease

P Wang, J Bai, X Liu, M Wang, X Wang, P Jiang - Veterinary research, 2020 - Springer
Porcine epidemic diarrhea virus (PEDV) causes lethal diarrhea in suckling piglets, leading
to severe economic losses worldwide. There is an urgent need to find new therapeutic …

Antidiarrheal effect of Psidium guajava L. extract in acute diarrhea: a systematic review

G Garrido, BB Garrido‐Suárez… - Journal of the …, 2024 - Wiley Online Library
Acute diarrheal diseases are a leading cause of childhood mortality and morbidity
worldwide. Psidium guajava has been globally used for its antidiarrheal potential. We …

Bis-benzylisoquinoline alkaloids inhibit porcine epidemic diarrhea virus in vitro and in vivo

S Dong, R Yu, X Wang, B Chen, F Si, J Zhou, C Xie… - Viruses, 2022 - mdpi.com
Porcine epidemic diarrhea virus (PEDV) belongs to the genus Alphacoronavirus of the
family Coronaviridae that causes severe diarrhea and high mortality in neonatal suckling …

Chemical constituents of the culture broth of Dentipellis fragilis and their anti-inflammatory activities

DW Ki, CW Kim, DC Choi, GW Oh, TP Doan, JY Kim… - Phytochemistry, 2023 - Elsevier
Seven undescribed compounds, dentipellinones A‒D (1, 2, 5, and 6), dentipellinol (3),
methoxyerinaceolactone B (4), and erinaceolactomer A (7), were isolated from the culture …

Antibiotic-Resistant Staphylococcus aureus Does Not Develop Resistance to Vanillic Acid and 2-Hydroxycinnamic Acid after Continuous Exposure in Vitro

D Keman, F Soyer - Acs Omega, 2019 - ACS Publications
Development of resistance to antibiotics is one of the major reasons of difficulties in
treatments of diseases caused by antibiotic-resistant bacteria, and this resistance makes the …

Targeting the PEDV 3CL protease for identification of small molecule inhibitors: an insight from virtual screening, ADMET prediction, molecular dynamics, free energy …

RK Pathak, WI Kim, JM Kim - Journal of Biological Engineering, 2023 - Springer
Background The porcine epidemic diarrhea virus (PEDV) represents a major health issue for
piglets worldwide and does significant damage to the pork industry. Thus, new therapeutic …

Integrative network pharmacology and in silico analyses identify the anti-omicron SARS-CoV-2 potential of eugenol

Y Liu - Heliyon, 2023 - cell.com
Eugenol as a natural product is the source of isoniazid, and purified eugenol is extensively
used in the cosmetics industry and the productive processes of edible spices. Accumulating …

Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and β-d-N4-hydroxycytidine

Y Xie, X Guo, T Hu, D Wei, X Ma, J Wu, B Huang… - Virologica Sinica, 2021 - Springer
Porcine epidemic diarrhea (PED) caused by porcine epidemic diarrhea virus (PEDV) is
widespread in the world. In recent years, the increased virulence of the virus due to viral …