ALOX12 encodes arachidonic acid 12-lipoxygenase that acts on different polyunsaturated
fatty acid substrates to produce biologically active lipid mediators including eicosanes and …

Down syndrome is the most common chromosomal abnormality among live-born infants.
Through full or partial trisomy of chromosome 21, Down syndrome is associated with …

Background Down syndrome (DS) clinical multisystem condition is generally considered the
result of a genetic imbalance generated by the extra copy of chromosome 21. Recent …

Background The main objective of this study was to describe the inflammatory status of
adolescents with Down syndrome (DS) and their relationship with adiposity. Methods Ninety …

Down syndrome (DS), caused by trisomy of chromosome 21 (HSA21), results in a broad
range of phenotypes. However, the determinants contributing to the complex and variable …

In day-to-day living, individuals are exposed to various environmentally hazardous
substances that have been associated with diverse diseases. Exposure to air pollutants can …

Aim. Aware that Down Syndrome patients present among their clinical characteristics
impaired immunity, the aim of this study is to identify the statistically significant differences in …

Immunological impairment is a condition that is often observed in individuals with Down
syndrome (DS). The immune response is modulated by pro‐and anti‐inflammatory cytokines …

Scar physique refers to the abnormal repair of skin injury in some people, which may easily
lead to keloid or hypertrophic scar. However, the mechanism of scar physique is still unclear …

Down syndrome (DS) or trisomy 21 is a genetic condition often accompanied by chronic
pain caused by congenital abnormalities and/or conditions, such as osteoarthritis, recurrent …