Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic …
Despite advances in breast cancer treatments and related 5-year survival outcomes,
metastatic breast cancer cures remain elusive. The current standard of care includes a …
metastatic breast cancer cures remain elusive. The current standard of care includes a …
Nano-based delivery systems for berberine: A modern anti-cancer herbal medicine
H Majidzadeh, M Araj-Khodaei, M Ghaffari… - Colloids and Surfaces B …, 2020 - Elsevier
Berberine (BBR) is an isoquinoline alkaloid belonging to the structural class of
protoberberines. BBR has been used in traditional medicine to treat diseases, such as type …
protoberberines. BBR has been used in traditional medicine to treat diseases, such as type …
[HTML][HTML] Nanotechnology-based combination therapy for overcoming multidrug-resistant cancer
M Zhang, E Liu, Y Cui, Y Huang - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
Multidrug resistance (MDR) is a major obstacle to successful cancer treatment and is crucial
to cancer metastasis and relapse. Combination therapy is an effective strategy for …
to cancer metastasis and relapse. Combination therapy is an effective strategy for …
Rising horizon in circumventing multidrug resistance in chemotherapy with nanotechnology
H Choudhury, M Pandey, TH Yin, T Kaur, GW Jia… - Materials Science and …, 2019 - Elsevier
Multidrug resistance (MDR) is one of the key barriers in chemotherapy, leading to the
generation of insensitive cancer cells towards administered therapy. Genetic and epigenetic …
generation of insensitive cancer cells towards administered therapy. Genetic and epigenetic …
[HTML][HTML] Combination cancer therapy using chimeric antigen receptor-engineered natural killer cells as drug carriers
The therapeutic limitations of conventional chemotherapeutic drugs include chemo-
resistance, tumor recurrence, and metastasis. Numerous nanoparticle-based active …
resistance, tumor recurrence, and metastasis. Numerous nanoparticle-based active …
Preparation and characterization of stable nanoliposomal formulations of curcumin with high loading efficacy: in vitro and in vivo anti-tumor study
Liposomal formulations were made using Solvent-assisted active loading technology
(SALT). Two formulations composed of HSPC: DPPG: Chol: DSPE-mPEG 2000 (PG …
(SALT). Two formulations composed of HSPC: DPPG: Chol: DSPE-mPEG 2000 (PG …
Microneedle‐based generation of microbubbles in cancer tumors to improve ultrasound‐assisted drug delivery
Production of local microbubbles (MBs) with dense distribution in tumor environment is
achieved by developing an integrated electrochemical stimulator on a microfabricated …
achieved by developing an integrated electrochemical stimulator on a microfabricated …
Micelles of d-α-Tocopheryl Polyethylene Glycol 2000 Succinate (TPGS 2K) for Doxorubicin Delivery with Reversal of Multidrug Resistance
T Hao, D Chen, K Liu, Y Qi, Y Tian, P Sun… - … Applied Materials & …, 2015 - ACS Publications
The purpose of this study is to investigate the ability of doxorubicin (DOX)-loaded d-α-
tocopheryl polyethylene glycol 2000 succinate (TPGS 2K) micelles to overcome MDR in …
tocopheryl polyethylene glycol 2000 succinate (TPGS 2K) micelles to overcome MDR in …
[HTML][HTML] Drug resistance reversal in ovarian cancer cells of paclitaxel and borneol combination therapy mediated by PEG-PAMAM nanoparticles
L Zou, D Wang, Y Hu, C Fu, W Li, L Dai, L Yang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Paclitaxel (PTX) is frequently suffered from multidrug resistance (MDR), resulting in lower
chemotherapeutic efficacy and even chemotherapy failure. To combine the P-glycolprotein …
chemotherapeutic efficacy and even chemotherapy failure. To combine the P-glycolprotein …
Understanding the implications of co-delivering therapeutic agents in a nanocarrier to combat multidrug resistance (MDR) in breast cancer
AD Fulfager, KS Yadav - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
Cancer is one of the leading causes of death worldwide. Breast cancer is the most prevalent
cancer amongst women which can be treated by chemotherapy. During chemotherapy …
cancer amongst women which can be treated by chemotherapy. During chemotherapy …