Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

The spatial regulation of protein translation is an efficient way to create functional and
structural asymmetries in cells. Recent research has furthered our understanding of how …

Messenger ribonucleoprotein (mRNP) granules are dynamic, self-assembling structures that
harbor non-translating mRNAs bound by various proteins that regulate mRNA translation …

Local translation allows spatial control of gene expression. Here, we performed a dual
protein-mRNA localization screen, using smFISH on 523 human cell lines expressing GFP …

All RNA species in yeast cells are subject to turnover. Work over the past 20 years has
defined degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs …

As highlighted by recent genome-wide analyses in diverse organisms and cell types,
subcellular targeting of mRNAs has emerged as a major mechanism for cells to establish …

In this review, we provide an overview of protein synthesis in the yeast Saccharomyces
cerevisiae. The mechanism of protein synthesis is well conserved between yeast and other …

Local translation allows for a spatial control of gene expression. Here, we use high-
throughput smFISH to screen centrosomal protein-coding genes, and we describe 8 human …

The formation of protein complexes is crucial to most biological functions. The cellular
mechanisms governing protein complex biogenesis are not yet well understood, but some …

Cells spatially organize their molecular components to carry out fundamental biological
processes and guide proper development. The spatial organization of RNA within the cell …