Endometriosis treatment: role of natural polyphenols as anti-inflammatory agents

V Tassinari, A Smeriglio, V Stillittano, D Trombetta… - Nutrients, 2023 - mdpi.com
Endometriosis is an estrogen-dependent common chronic inflammatory disease defined by
the presence of extrauterine endometrial tissue that promotes pelvic pain and fertility …

The role of progesterone receptors in breast cancer

Z Li, H Wei, S Li, P Wu, X Mao - Drug design, development and …, 2022 - Taylor & Francis
The progesterone receptor (PR) modulates estrogen receptors α (ERα) action in breast
cancer; it is an upregulated target gene of ER, and its expression is dependent on estrogen …

Sex steroid hormones and DNA repair regulation: Implications on cancer treatment responses

P Rangsrikitphoti, DC Marquez-Garban… - The Journal of Steroid …, 2023 - Elsevier
The role of sex steroid hormones (SSHs) has been shown to modulate cancer cytotoxic
treatment sensitivity. Dysregulation of DNA repair associated with genomic instability …

ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation

C Wang, Z Liu, Y Zeng, L Zhou, Q Long, IU Hassan… - EMBO …, 2024 - embopress.org
The dorsoventral gradient of BMP signaling plays an essential role in embryonic patterning.
Zinc Finger SWIM-Type Containing 4 (zswim4) is expressed in the Spemann-Mangold …

Genetics, treatment, and new technologies of hormone receptor-positive breast cancer

W Sebastian, L Forchette, K Donoughe, Y Lun… - Cancers, 2023 - mdpi.com
Simple Summary In this review paper, we focused on the discussion of various important
aspects of hormone receptor (HR)-positive breast cancer, including HR structure and …

Discovery of drug targets based on traditional Chinese medicine microspheres (TCM-MPs) fishing strategy combined with bio-layer interferometry (BLI) technology

H Zhang, J Yao, G Xiao, J Xie, S Mao, C Sun, J Yao… - Analytica Chimica …, 2024 - Elsevier
Target discovery of natural products is a key step in the development of new drugs, and it is
also a difficult speed-limiting step. In this study, a traditional Chinese medicine microspheres …

[PDF][PDF] ZSWIM4 regulates early embryonic patterning and BMP signaling pathway by promoting nuclear Smad1 degradation

C Wang, Z Liu, Y Zeng, L Zhou, Q Long, HI Ul, Y Zhang… - 2022 - scholar.archive.org
The dorsoventral gradient of BMP signaling plays an essential role in embryonic patterning.
We found that Zinc Finger SWIM-Type Containing 4 (zswim4) is expressed in the Spemann …

Regulation of estrogen receptor alpha by promoter methylation, alternative splicing and microRNA

J Albrecht - 2024 - portal.research.lu.se
Breast cancer, a common and often aggressive malignancy, presents significant challenges
due to its ability to develop resistance to therapies. This resistance is intricately linked to the …