The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives
C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
Drug resistance and tolerance in fungi
J Berman, DJ Krysan - Nature Reviews Microbiology, 2020 - nature.com
Systemic fungal infections pose a serious clinical problem. Treatment options are limited,
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …
Immune regulation by fungal strain diversity in inflammatory bowel disease
The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial
community colonizing the mammalian gastrointestinal tract and has an important role in …
community colonizing the mammalian gastrointestinal tract and has an important role in …
[HTML][HTML] Candida albicans and oral carcinogenesis. A brief review
M Di Cosola, AP Cazzolla, IA Charitos, A Ballini… - Journal of Fungi, 2021 - mdpi.com
Current medical knowledge and research on patients' management are still evolving, and
several protocols on minimizing risk of infection by Candida spp. among the population have …
several protocols on minimizing risk of infection by Candida spp. among the population have …
Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs
RT Todd, A Selmecki - Elife, 2020 - elifesciences.org
Previously, we identified long repeat sequences that are frequently associated with genome
rearrangements, including copy number variation (CNV), in many diverse isolates of the …
rearrangements, including copy number variation (CNV), in many diverse isolates of the …
Changes in fungal taxonomy: mycological rationale and clinical implications
AM Borman, EM Johnson - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Numerous fungal species of medical importance have been recently subjected to and will
likely continue to undergo nomenclatural changes as a result of the application of molecular …
likely continue to undergo nomenclatural changes as a result of the application of molecular …
Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease
FM Anderson, ND Visser, KR Amses… - Plos …, 2023 - journals.plos.org
Candida albicans is a frequent colonizer of human mucosal surfaces as well as an
opportunistic pathogen. C. albicans is remarkably versatile in its ability to colonize diverse …
opportunistic pathogen. C. albicans is remarkably versatile in its ability to colonize diverse …
The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and …
VE Glazier, J Kramara, T Ollinger, NV Solis… - MBio, 2023 - Am Soc Microbiol
Candida albicans is a diploid human fungal pathogen that displays significant genomic and
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
Interspecific hybridization as a driver of fungal evolution and adaptation
Cross-species gene transfer is often associated with bacteria, which have evolved several
mechanisms that facilitate horizontal DNA exchange. However, the increased availability of …
mechanisms that facilitate horizontal DNA exchange. However, the increased availability of …
[HTML][HTML] Immunosurveillance of Candida albicans commensalism by the adaptive immune system
M Swidergall, S LeibundGut-Landmann - Mucosal immunology, 2022 - Elsevier
The fungal microbiota (mycobiota) is an integral part of the microbial community colonizing
the body surfaces and is involved in many key aspects of human physiology, while an …
the body surfaces and is involved in many key aspects of human physiology, while an …