The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease

MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

Maternal obesity and the impact of associated early-life inflammation on long-term health of offspring

M Denizli, ML Capitano, KL Kua - Frontiers in cellular and infection …, 2022 - frontiersin.org
The prevalence of obesity is increasingly common in the United States, with~ 25% of women
of reproductive age being overweight or obese. Metaflammation, a chronic low grade …

[HTML][HTML] SARS-CoV-2 placentitis, stillbirth, and maternal COVID-19 vaccination: clinical–pathologic correlations

DA Schwartz, SB Mulkey, DJ Roberts - American journal of obstetrics and …, 2023 - Elsevier
Stillbirth is a recognized complication of COVID-19 in pregnant women that has recently
been demonstrated to be caused by SARS-CoV-2 infection of the placenta. Multiple global …

[HTML][HTML] Experimental human placental models for studying uptake, transport and toxicity of micro-and nanoplastics

HM Dusza, J van Boxel, MBM van Duursen… - Science of The Total …, 2023 - Elsevier
Micro-and nanoplastics (MNPs) are ubiquitous in the environment and have recently been
found in human lungs, blood and placenta. However, data on the possible effects of MNPs …

Adverse prenatal exposures and fetal brain development: insights from advanced fetal magnetic resonance imaging

J De Asis-Cruz, N Andescavage… - Biological Psychiatry …, 2022 - Elsevier
Converging evidence from clinical and preclinical studies suggests that fetal vulnerability to
adverse prenatal exposures increases the risk for neuropsychiatric diseases such as autism …

Interdisciplinary fetal-neonatal neurology training applies neural exposome perspectives to neurology principles and practice

MS Scher - Frontiers in neurology, 2024 - frontiersin.org
An interdisciplinary fetal-neonatal neurology (FNN) program over the first 1,000 days
teaches perspectives of the neural exposome that are applicable across the life span. This …

[HTML][HTML] The maternal-placental-fetal interface: Adaptations of the HPA axis and immune mediators following maternal stress and prenatal alcohol exposure

C Ruffaner-Hanson, S Noor, MS Sun, E Solomon… - Experimental …, 2022 - Elsevier
This review addresses underlying physiological, cellular, and molecular factors that alter the
developing fetal brain stress circuits and responses of the hypothalamic-pituitary-adrenal …

Generating functional multicellular organoids from human placenta villi

L Huang, Z Tu, L Wei, W Sun, Y Wang, S Bi… - Advanced …, 2023 - Wiley Online Library
The interaction between trophoblasts, stroma cells, and immune cells at the maternal–fetal
interface constitutes the functional units of the placenta, which is crucial for successful …

[HTML][HTML] Criteria for placental examination for obstetrical and neonatal providers

DJ Roberts, RN Baergen, TK Boyd, CK Carreon… - American journal of …, 2023 - Elsevier
Pathologic examination of the placenta can provide insight into likely (and unlikely) causes
of antepartum and intrapartum events, diagnoses with urgent clinical relevance, prognostic …

[HTML][HTML] Temporal Dynamics of Oxidative Stress and Inflammation in Bronchopulmonary Dysplasia

M Teng, TJ Wu, X Jing, BW Day, KA Pritchard Jr… - International Journal of …, 2024 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common lung complication of prematurity.
Despite extensive research, our understanding of its pathophysiology remains limited, as …