Phytobioactive compounds as therapeutic agents for human diseases: A review

M Riaz, R Khalid, M Afzal, F Anjum… - Food Science & …, 2023 - Wiley Online Library
Phytobioactive compounds are plant secondary metabolites and bioactive compounds
abundantly present in medicinal plants and have remarkable therapeutic potential. Oxidative …

A review exploring therapeutic worth of 1, 3, 4-oxadiazole tailored compounds

G Verma, MF Khan, W Akhtar, MM Alam… - Mini Reviews in …, 2019 - ingentaconnect.com
1, 3, 4-Oxadiazole, a five-membered aromatic ring can be seen in a number of synthetic
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …

[HTML][HTML] In vitro antimicrobial evaluation, single-point resistance study, and radiosterilization of novel pyrazole incorporating thiazol-4-one/thiophene derivatives as …

HA Mohamed, YA Ammar, GAM Elhagali, HA Eyada… - ACS …, 2022 - ncbi.nlm.nih.gov
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …

In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual …

H Ali Mohamed, YA Ammar, G AM Elhagali… - ACS …, 2022 - ACS Publications
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …

Bio-oriented synthesis and molecular docking studies of 1, 2, 4-triazole based derivatives as potential anti-cancer agents against HepG2 cell line

N Akhter, S Batool, SG Khan, N Rasool, F Anjum… - Pharmaceuticals, 2023 - mdpi.com
Triazole-based acetamides serve as important scaffolds for various pharmacologically active
drugs. In the present work, structural hybrids of 1, 2, 4-triazole and acetamides were …

[HTML][HTML] A facile synthesis of 1, 3, 4-oxadiazole-based carbamothioate molecules: Antiseizure potential, EEG evaluation and in-silico docking studies

N Rasool, Z Razzaq, SG Khan, S Javaid… - Arabian Journal of …, 2023 - Elsevier
In present work, a series of novel structural hybrids of 1, 3, 4-oxadiazole and carbamothioate
was designed by chemical modification of 2-(4-isobutylphenyl) propanoic acid. Target …

Design, synthesis, and antimicrobial behavior of novel oxadiazoles containing various N‐containing heterocyclic pendants

D Zeng, MW Wang, M Xiang, LW Liu… - Pest Management …, 2020 - Wiley Online Library
BACKGROUND The gradually elevated outbreak of plant bacterial diseases severely limits
agricultural products and small amounts of pesticides can manage them. Our group has …

Ultrasound assisted synthesis and in silico modelling of 1, 2, 4-triazole coupled acetamide derivatives of 2-(4-Isobutyl phenyl) propanoic acid as potential anticancer …

S Mahmood, SG Khan, A Rasul, JB Christensen… - Molecules, 2022 - mdpi.com
The development of an economical method for the synthesis of biologically active
compounds was the major goal of this research. In the present study, we have reported the …

Selenium-N-heterocyclic carbene (Se-NHC) complexes with higher aromaticity inhibit microbes: synthesis, structure, and biological potential

A Kamal, MA Iqbal, HN Bhatti… - Journal of Coordination …, 2022 - Taylor & Francis
The synthesis of five selenium complexes bearing imidazole-based N-heterocyclic carbene
ligands (Se-NHC) are reported. The adducts were characterized by elemental and …

Synthesis, characterization and biological evaluation of Bis-benzimidazolium salts and their silver(I)-N-heterocyclic carbene complexes

RY Nadeem, M Yaqoob, WS Yam, RA Haque… - Medicinal Chemistry …, 2022 - Springer
Azolium salts are stable sources of N-heterocyclic carbenes (NHCs), an emerging class of
ligands. Due to prominent properties, they have versatile applications. In the current study …