Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission

G Livingston, J Huntley, KY Liu, SG Costafreda… - The Lancet, 2024 - thelancet.com
Executive summary The 2024 update of the Lancet Commission on dementia provides new
hopeful evidence about dementia prevention, intervention, and care. As people live longer …

Psychosis in Alzheimer disease—mechanisms, genetics and therapeutic opportunities

Z Ismail, B Creese, D Aarsland, HC Kales… - Nature Reviews …, 2022 - nature.com
Psychosis is a common and distressing symptom in people with Alzheimer disease, and few
safe and effective treatments are available. However, new approaches to symptom …

Exploring links between psychosis and frontotemporal dementia using multimodal machine learning: dementia praecox revisited

N Koutsouleris, C Pantelis, D Velakoulis… - JAMA …, 2022 - jamanetwork.com
Importance The behavioral and cognitive symptoms of severe psychotic disorders overlap
with those seen in dementia. However, shared brain alterations remain disputed, and their …

Characteristics of very late-onset schizophrenia-like psychosis as prodromal dementia with Lewy bodies: a cross-sectional study

H Kanemoto, Y Satake, T Suehiro, D Taomoto… - Alzheimer's Research & …, 2022 - Springer
Background This study aimed to identify cases of potential prodromal DLB in very late-onset
schizophrenia-like psychosis (VLOSLP), using indicative biomarkers of dementia with Lewy …

A longitudinal study of late-life psychosis and incident dementia and the potential effects of race and cognition

Z Ismail, M Ghahremani, M Amlish Munir… - Nature Mental …, 2023 - nature.com
Later-life psychotic symptoms are meaningful and are associated with adverse outcomes.
Psychosis is an important domain in mild behavioural impairment (MBI), a syndrome that …

Psychiatric disorders and risk of subsequent dementia: systematic review and metaanalysis of longitudinal studies

J Stafford, WT Chung, A Sommerlad… - … Journal of Geriatric …, 2022 - Wiley Online Library
Objectives Although psychiatric disorders have been found to be associated with increased
risk of dementia, previous findings are mixed, and the nature of these relationships remains …

Non-affective psychotic disorders and risk of dementia: a systematic review and meta-analysis

S El Miniawi, V Orgeta, J Stafford - Psychological Medicine, 2022 - cambridge.org
Non-affective psychotic disorders have been associated with an increased risk of
developing dementia. However, research in this area remains limited, highlighting the need …

Latelife onset psychotic symptoms and incident cognitive impairment in people without dementia: Modification by genetic risk for Alzheimer's disease

B Creese, R Arathimos, D Aarsland… - … Research & Clinical …, 2023 - Wiley Online Library
Introduction Latelife onset psychosis is associated with faster progression to dementia in
cognitively normal people, but little is known about its relationship with cognitive impairment …

The Janus face of antipsychotics in glial cells: Focus on glioprotection

I Schmitz, A da Silva, LD Bobermin… - Experimental …, 2023 - journals.sagepub.com
Antipsychotics are commonly prescribed to treat several neuropsychiatric disorders,
including schizophrenia, mania in bipolar disorder, autism spectrum disorder, delirium, and …

Crossroad between current knowledge and new perspective of diagnostic and therapy of late-onset schizophrenia and very late-onset schizophrenia-like psychosis …

O Stȩpień-Wyrobiec, M Nowak, G Wyrobiec… - Frontiers in …, 2022 - frontiersin.org
Schizophrenia is a chronic, highly individualized disease with many symptoms that can
occur with varying severity in different patients. Schizophrenia affects 1% of the population …